CLERC, THIERRY,JUNQUERO, DIDIER,PEREZ, MICHEL,AUTIN, JEAN-MARIE
申请号：
EP12711677.0
公开号：
EP2694477B1
申请日:
2012.04.04
申请国别(地区):
EP
年份:
2015
代理人:
摘要：
The present invention relates to novel alkyl thioethers for the preparation of a medicament intended to prevent or to treat a disorder due to a dysfunction of the sebaceous glands in humans or animals. The compounds according to the present invention exert a strong inhibition of acyl CoA: cholesterol O-acyl transferase (ACAT): (I) in which - R1 represents a hydroxyl or amino group, - R2 represents a hydrogen or a methyl radical, - A represents a group chosen from: (II) - n represents an integer from 5 to 13.
