Claudiu SUPURAN,Shoukat DEDHAR,Paul C. MCDONALD,Fabrizio CARTA
申请号:
US15270742
公开号:
US20170007627A1
申请日:
2016.09.20
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Therapeutic ureido-sulfonamide compositions having compounds with the formulaR-Q-Ar—SO2NH2are disclosed, which compounds selectively inhibit CAIX and CAXII, and which are effective to inhibit hypoxic tumor growth, suppress metastases, and impair and deplete cancer stem cells in mammals.