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Inactivating pathogens with oxidizing agents for vaccine production
专利权人:
Shirley Villadiego;Mark K. Slifka;Paul Yoshihara;Erika Hammarlund
发明人:
Mark K. Slifka,Shirley Villadiego,Erika Hammarlund,Paul Yoshihara
申请号:
US13405082
公开号:
US08716000B2
申请日:
2012.02.24
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present disclosure provides methods for producing a vaccine composition containing a pathogen that is rendered noninfectious by exposure to hydrogen peroxide. The methods disclosed herein are suitable for the preparation of vaccines for a wide variety of pathogens, including viruses, bacteria and parasites. The disclosure also provides vaccine compositions (medicaments) containing a pathogen inactivated by exposure to hydrogen peroxide. Methods for eliciting an immune response in a subject by administering vaccine compositions containing a hydrogen peroxide inactivated pathogen are also provided.
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