PALIWAL SUNIL,SUNIL PALIWAL,REICHARD GREGORY A.,GREGORY A. REICHARD,WANG CHENG,CHENG WANG,XIAO DONG,DONG XIAO,TSUI HON-CHUNG,HON-CHUNG TSUI,SHIH NENG-YANG,NENG-YANG SHIH,ARREDONDO JUAN D.,JUAN D. ARRE,JUAN D. ARREDONDO,ARREDONDO JU
申请号：
PL370841
公开号：
PL216664B1
申请日:
2002.12.17
申请国别(地区):
PL
年份:
2014
代理人:
摘要：
A NK 1 antagonist having the formula (I), wherein Ar 1 and Ar 2 are optionally substituted phenyl or heteroaryl, X 1 is an ether, thio or imino linkage, R 4 and R 5 are not both H or alkyl, and the remaining variables are as defined in the specification, useful for treating a number of disorders, including emesis, depression, anxiety and cough. Pharmaceutical compositions. Methods of treatment and combinations with other agents are also disclosed.
