Insecticide composition where the active ingredient includes a combination of at least one synthetic insecticidal molecule from the neonicotinoïd family, and at least one synergistic agent, which is chosen among the insect repellent agents and present in the composition at a molar ratio of the synergistic agent to the synthetic insecticidal molecule in the composition comprised between 0.001 and 0.2. The insecticide includes a synergistic combination of DEET or IR3535® with thiaclopride or thiamethoxam that are more effective at low doses.