COMPOSES INTERAGISSANT AVEC LA SUPERFAMILLE RAS DESTINES A ETRE UTILISES DANS LE TRAITEMENT DE CANCERS, DE MALADIES INFLAMMATOIRES, DE RASOPATHIES ET DE MALADIES FIBROTIQUES
HADARI, YARON R.,CARTA, LUCA,SCHMERTZLER, MICHAEL,WILLIAMS, THERESA M.,REYNOLDS, CHARLES H.,HUTCHESON, REBECCA
申请号：
CA3066939
公开号：
CA3066939A1
申请日:
2018.06.20
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
Provided herein are methods and compositions for treating cancers, inflammatory diseases, rasopathies, and fibrotic disease involving aberrant Ras superfamily signaling through the binding of compounds to the GTP binding domain of Ras superfamily proteins including, in certain cases, K-Ras and mutants thereof, and a novel method for assaying such compositions.
