PROBLEM TO BE SOLVED: To provide pharmaceutical compositions for treating vertigo of various origin, motion sickness, and autonomic vascular dystonia.SOLUTION: A pharmaceutical composition contains an activated-potentiated form of an antibody to endothelial NO-synthase, and an activated-potentiated form of an antibody to brain specific protein S-100. The activated-potentiated form of the antibody to the brain specific protein S-100 is against the entire bovine brain specific protein S-100, and preferably the activated-potentiated form of the antibody to endothelial NO-synthase is against the entire human or bovine NO-synthase.SELECTED DRAWING: None【課題】種々の起源の回転性めまい、動揺病及び自律神経血管ジストニアを治療するための医薬品組成物の提供。【解決手段】内皮NO合成酵素に対する活性化増強型抗体と、脳特異的タンパク質S-100に対する活性化増強型抗体とを含む組み合わせ医薬組成物。脳特的タンパク質S-100に対する活性化増強型抗体がウシ脳特異的タンパク質S-100全体に対するものであり内皮NO合成酵素に対する活性化増強型抗体がヒト又はウシNO合成酵素全体に対することが好ましい医薬組成物。【選択図】なし