System and method of dynamically presenting visual representations of a target volume in an anatomical context to an operator-user of a charged particle radiation therapy system. The visual representations are integrated as a part of a treatment console graphical user interface (GUI) and presented as a part of a holistic view of treatment information. The visual representations are digitally reconstructed radiographs (DRRs) constructed based on anatomical images captured before the therapy session, or alternatively during a treatment session using an imaging system attached to the radiation treatment system. In an online mode, the on-screen visual representations are rendered in synchronization with the irradiation delivery process.