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Vascular tissue and method for producing the same
专利权人:
国立大学法人;千葉大学
发明人:
関 実,山田 真澄,岩瀬 優輝
申请号:
JP2014531532
公开号:
JP6241890B2
申请日:
2013.06.20
申请国别(地区):
JP
年份:
2017
代理人:
摘要:
Provided is a novel technique for producing functional vascular tissue having a layered structure, a hollow structure, and a branched structure combined by a simple operation, which requires neither the complex position control devices or operations that are essential to existing techniques for the ex vivo production of vascular tissue at least partially comprising cells, nor a convoluted multiple-stage process. The vascular tissue obtained by said novel technique is also provided. A method for producing the vascular tissue is used by which a first aqueous sodium alginate solution, in which cells have been suspended, is introduced into a channel structure comprising a material that contains polyvalent metal cations or that contains an inorganic salt containing the polyvalent metal cations, a first alginate hydrogel layer containing the cells is formed on the inner walls of the channel structure, and thereafter the first aqueous sodium alginate solution which remains in the channel structure and has not gelated is removed.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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