The invention relates to medicine, particularly to hepatology.According to the invention, the claimed method consists in that it is carried out the intensive therapy, including the parenteral administration of antibiotics, hepatoprotectors, plasma, amino acids, rheological, disaggregating and diuretic agents, and additionally is carried out the laparocentesis with the evacuation of 3…5 L of contaminated ascitic fluid, then through laparoscopic approach under visual control is installed a drain in the inferior floor of abdomen, through which is pumped CO2 in the amount of 3000…5000 cm3, bubbling it through the remaining ascitic fluid for 3…5 min, afterwards the introduced gas is evacuated through the upper trocar, then through the drain is pumped O2 in the amount of 1000…3000 cm3, bubbling it through the remaining ascitic fluid for 2…3 min, afterwards is evacuated the rest of the ascitic fluid, and through the drain is successively introduced 2% lidocaine solution in an amount of 20…30 ml, dexamethasone 8…16 mg, diluted in 100…200 ml of 0.9% NaCl solution, lydase 370…640 U, diluted in 200…500 ml of 0.9% NaCl solution, an antibiotic from the group of cephalosporins and an antimicrobial agent from the group of fluoroquinolones, diluted in 200…500 ml of 0.9% NaCl solution, the procedure for administration of drugs through the drain is performed daily, for 3…5 days.Invenţia se referă la medicină, în special la hepatologie.Conform invenţiei, metoda revendicată constă în aceea că se efectuează terapia intensivă care include administrarea parenterală a antibioticelor, hepatoprotectoarelor, plasmei, aminoacizilor, preparatelor reologice, dezagregante şi diuretice, iar suplimentar se efectuează laparocenteza cu evacuarea a 3…5 L de lichid ascitic contaminat, apoi prin abord laparoscopic sub control vizual se instalează un dren în etajul abdominal inferior, prin care se insuflă CO2 în cantitate de 3000…5000 cm3, barbotându-l prin lichidul ascitic restant timp de 3…5 min, după