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SUBSTITUTED ACYLGUANIDINE DERIVATIVES (AS AMENDED)
专利权人:
Isao Kinoyama
发明人:
Isao Kinoyama,Yohei Koganemaru,Takehiro Miyazaki,Takuya Washio
申请号:
US13148448
公开号:
US20120041036A1
申请日:
2010.02.08
申请国别(地区):
US
年份:
2012
代理人:
摘要:
An object of the present invention is to provide an excellent agent for treating or preventing dementia, schizophrenia based on serotonin 5-HT5A receptor modulating action.It was discovered that acylguanidine derivatives, in which the guanidine is bonded to one ring of a naphthalene via a carbonyl group and a cyclic group is bonded to the other ring thereof, exhibit potent the 5-HT5A receptor modulating action and excellent pharmacological actions based on the action. The present invention is useful as an excellent agent for treating or preventing dementia, schizophrenia, bipolar disorder or attention deficit hyperactivity disorder.
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