anthracycline derivative conjugates, polymeric carrier, antibody, peptide or protein, t- [cho] m carrier, pharmaceutical compositions, methods of treating cancer or cell proliferation disorders, anthracycline derivative, drug-antibody conjugate compound, use, article of Manufacture and Method of Production of a Drug-Antibody Conjugate Compound "
ANDREW POLSON,BARBARA VALSASINA,ITALO BERIA,JOHN A. FLYGARE,MATTEO SALSA,MICHELE CARUSO,PAUL POLAKIS,RITA PEREGO,SUSAN D. SPENCER,VITTORIA LUPI
申请号:
BRPI0910810
公开号:
BRPI0910810A2
申请日:
2009.07.14
申请国别(地区):
BR
年份:
2019
代理人:
摘要:
The present invention relates to conjugates of therapeutically useful anthracyclines with carriers such as polyclonal and monoclonal antibodies, proteins or peptides of natural or synthetic origin; methods for their preparation, pharmaceutical composition containing them and use thereof in treating certain mammalian tumors.