Peptide compounds of general formula (I) R1-(AA)n-X1-Ser-Thr-Pro-X2-(AA)p-R2 were developed that restore the circadian rhythm and resynchronize the biological clock of skin cells. Cosmetic or pharmaceutical compositions that include at least one peptide of general formula (I) in a cosmetically or dermatologically acceptable medium, and a cosmetic treatment method for restoring the circadian rhythm and resynchronising the biological clock of cells to reduce the dysfunctions caused by jet lag and/or nightshift work and/or to prevent or treat the cutaneous signs of aging were also developed.本発明は、化粧品及び皮膚科学の分野に関する。本発明は、サーカディアンリズムを回復するための、及び皮膚細胞の生物時計を再同調するための、一般式（Ｉ）：Ｒ１－(ＡＡ)ｎ－Ｘ１－Ｓｅｒ－Ｔｈｒ－Ｐｒｏ－Ｘ２－（ＡＡ）ｐ－Ｒ２のペプチド化合物に関し、並びに老化の効果を予防及び修正するための化粧品及び／または製薬におけるそれらの使用に関する。
