DOLLINGER, HORST,MARTYRES, DOMNIC,MACK, JUERGEN,GOEGGEL, ROLF,JUNG, BIRGIT,NICKOLAUS, PETER
申请号:
CA2652840
公开号:
CA2652840C
申请日:
2007.05.15
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The invention relates to the use of the pteridines of formula 1(see formula 1)whereinR1 denotes a group selected from the group consisting of pyrrolidinyl andthiomorpholinyl;and whereinR2 denotes piperazinyl,and whereinR3 denotes NR3.1R3.2 or OR3.1, wherein R3.1 and R3.2 are defined herein,or a pharmacologically acceptable salt, diasteromer, enantiomer, racemate,hydrate or solvatethereof,for preparing a medicament for the prevention or treatment of inflammatory orobstructivediseases such as COPD, asthma, idiopathic pulmonary fibrosis, rheumatoidarthritis andulcerative colitis.