CHRISTIAN LERNER,DANIEL HUNZIKER,PHILIPPE PFLIEGER,PIUS WALDMEIER,ULRIKE OBST SANDER,WERNER MUELLER
申请号：
BRPI1010523
公开号：
BRPI1010523A2
申请日:
2010.03.23
申请国别(地区):
BR
年份:
2016
代理人:
摘要：
The present invention relates to compounds of formula I wherein R1a to R1c, R2, R3 and R5 are as defined in the description and claims and R4 signifies a bicyclic heteroaryl group or a cyanophenyl group, as well as pharmaceutically acceptable salts thereof. The compounds are glucocorticoid receptor antagonists useful for the treatment and/or prevention of diseases such as diabetes, dyslipidemia, obesity, hypertension, cardiovascular diseases, adrenal imbalance or depression.
