William DRELL;Jonathan MOSS;Michael F. ROIZEN;Joseph F. FOSS;Chun-Su YUAN
发明人:
Joseph F. FOSS,Michael F. ROIZEN,Jonathan MOSS,Chun-Su YUAN,William DRELL
申请号:
US13230193
公开号:
US20120190702A1
申请日:
2011.09.12
申请国别(地区):
US
年份:
2012
代理人:
摘要:
A method of preventing or treating constipation in a patient who has been chronically taking opioids, the method comprising administering a quaternary derivative of noroxymorphone in an amount sufficient to prevent or treat the side effect in the patient, but which amount would be insufficient to treat a patient with the same opioid-induced side effect who had not chronically been administered opioids.