R. Kent Dyer, Jr.;Jack V. D. Hough;R. Kent Dyer; Jr.
发明人:
R. Kent Dyer, Jr.,Jack V. D. Hough
申请号：
US12148738
公开号：
US08303990B2
申请日:
2008.04.22
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Diagnosing or treating a human ear includes transporting a conjugated nanoparticle or a magnetically responsive nanoparticle into a human's middle or inner ear. Otologic nanophoresis includes electrically, magnetically or electromagnetically driving a nanoparticle through a membrane of the ear, including a tympanic membrane, a round window membrane, an oval window membrane, or a circulatory membrane. An otologic diagnostic device includes a nanoparticle conjugated with a material selected from the group consisting of lipids, proteins, growth factors, growth hormones, antioxidants, free radical scavengers, steroid preparations, and metabolically active substances； an otologic therapeutic device includes the same categories of substances and chemotherapeutic drugs. Another otologic composition includes a nanoparticle conjugated with a substance perceptible to magnetic resonance imaging.
