VLAHOV, IONTCHO RADOSLAVOV,LEAMON, CHRISTOPHER PAUL
申请号：
CA2617660
公开号：
CA2617660C
申请日:
2006.08.18
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
Described herein are compounds, pharmaceutical compositions and methods fortreating pathogenic cell populations in a patient. The compounds describedherein include conjugates of a plurality of cytotoxic drugs and vitaminreceptor binding ligands. The plurality of drugs may be the same or different.Similarly, the vitamin receptor binding ligands may be the same or different.The conjugates also include a linker that is formed from one or more spacerlinkers, heteroatom linkers, and releasable linkers.
