연세대학교 산학협력단;INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY;EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION;이화여자대학교 산학협력단
发明人:
YOON, Yeo Joon,윤여준,CHEONG, Eunji,정은지,CHO, Seung-Woo,조승우,SONG, Myoung-Chong,송명종,BEOM, Ji Yoon,범지윤,JUNG, Jin A,정진아,LEE, Jong Seung,이종승,LEE, Heon-Joo,이헌주
申请号：
KRKR2019/017523
公开号：
WO2020/122611A1
申请日:
2019.12.11
申请国别(地区):
KR
年份:
2020
代理人:
摘要：
The present invention relates to a novel compound usable as a main ingredient of a composition for stimulating hair growth, and to a use of same in hair growth stimulation, wherein the compound is 9-deoxo-31-O-demethyl-prolyl-FK506, 9-deoxo-36,37-dihydro-FK506, 31-O-demethyl-36,37-dihydro-FK506, 9-deoxo-31-O-demethyl-36,37-dihydro-FK506, 9-deoxo-FK520, 31-O-demethyl-FK520, 9-deoxo-31-O-demethyl-FK520, 9-deoxo-FK523, or 9-deoxo-31-O-demethyl-FK523.La présente invention concerne un nouveau composé pouvant être utilisé comme ingrédient principal d'une composition pour stimuler la croissance des cheveux, et une utilisation de celui-ci dans la stimulation de la pousse des cheveux, le composé étant le 9-9-déoxo-31-O-déméthyl-prolyl-FK506, le 9-déoxo-36,37-dihydro-FK506, 31-O-déméthyl-36,37-dihydro-FK506, le 9-déoxo-31-O-déméthyl-36,37-dihydro-FK506, le 9-déoxo-FK520, 31-O-déméthyl-FK520, le 9-déoxo-31-O-déméthyl-FK520, le 9-déoxo-FK523, ou le 9-déoxo-31-O-déméthyl-FK523.본 발명은 발모 촉진용 조성물의 주요 성분으로 활용이 가능한 신규 화합물 9-deoxo-31-O-demethyl-prolyl-FK506, 9-deoxo-36,37-dihydro-FK506, 31-O-demethyl-36,37-dihydro-FK506, 9-deoxo-31-O-demethyl-36,37-dihydro-FK506, 9-deoxo-FK520, 31-O-demethyl-FK520, 9-deoxo-31-O-demethyl-FK520, 9-deoxo-FK523, 또는 9-deoxo-31-O-demethyl-FK523의 제조 및 이의 발모 촉진용도에 관한 것이다.
