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Anti infectious agents and their use
专利权人:
ABBOTT LABORATORIES
发明人:
WAGNER ROLF,TUFANO MICHAEL D.,STEWART KENT D.,ROCKWAY TODD W.,RANDOLPH JOHN T.,PRATT JOHN K.,MOTTER CHRISTOPHER E.,MARING CLARENCE J.,LONGENECKER KENTON L.,LIU YAYA,LIU DACHUN,KRUEGER ALLAN C.,KATI WA
申请号:
ARP120102873
公开号:
AR087472A2
申请日:
2012.08.06
申请国别(地区):
AR
年份:
2014
代理人:
摘要:
It involves: (a) compounds and salts that are mainly inhibited by hexachlorobenzene; (b) intermediates that contribute to the preparation of these compounds and salts; (c) compounds containing these compounds and salts; (d) methods of manufacturing these intermediates, compounds, salts and compounds; (e) The method of using these compounds, salts and compounds; and (f) a group of elements composed of these compounds, salts and compounds. Claim 1: a compound or a salt thereof, characterized in that the compound structurally corresponds to the formula (1);- - * - - is selected from the group consisting of carbon-carbon single bond and carbon-carbon double bond; R1 is selected from the group consisting of hydrogen, methyl, and nitrogen protecting group; R2 is selected from the group consisting of hydrogen, halo, hydroxy, methyl, cyclopropyl, and cyclobutyl; R3 is selected from the group consisting of hydrogen, halo, oxo, and methyl; R4 is selected from the group consisting of halo, alkyl, alkenyl, alkynyl, nitro, cyano, azido, alkyloxy, alkenyloxy, alkynyloxy, amino, aminocarbonyl, aminosulfonyl, alkylsulfonyl, carbocyclyl, and heterocyclyl, where: (a) amino groups , aminocarbonyl,and aminosulfonyl are optionally substituted with: (i) one or two substituents independently selected from the group consisting of alkyl, alkenyl, alkynyl, and alkylsulfonyl, or (ii) two substituents which, together with the amino nitrogen, form a single ring heterocyclyl, and (b) the alkyl, alkenyl, alkynyl, alkyloxy, alkenyloxy, alkynyloxy, and alkylsulfonyl groups are optionally substituted with one or more substituents independently selected from the group consisting of halo, oxo, nitro, cyano, azido, hydroxy, amino, alkyloxy, trimethylsilyl, carbocyclyl, and heterocyclyl,Alternative: amines are replaced by: (I) one or two alternatives selected separately from a group consisting of asphalt, binder, tar, tar, carbohydrate, isocyclocyanide, carbohydrate and isocyclocyanide, or (II) two alte
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