It has been found that these compounds and their salts hinder the binding of the Bet protein family containing bromine A.For instanceAcetyllysine residues andTherefore,They can be used in treatment.For instanceIn the treatment of self-immunity and inflammation,For example, rheumatoid arthritisAnd cancer Claim 1: A formula compound (1),Or the salt in it.R1 represents an equation compound (2) or (3)；R2 is hydrogen1. C83218331 and 832626 leased land；Alcoxi C832188331636262；Cyoquilo C83238C83318327；E. heterocyclic electrolysis O-CHR83090 (CH832228) 7580； R8310；Each cubic meter is selected separately from the halogen group.- um.1. Apartment No. C83218331；Alcoxi C8321883318323237A,- No. 8322；- Conr8311； - R831222；- No. 8311； Cor 831222；- OCOR831222,- CO83228R831222,- SO8322； No. 8311； R831222；- No. 8311； No. SO8322； No. 831222；- SO83228R831222,- R831222,- No. 8311； - No. 831222；The condition is, when A is 2,R3 is selected from the halogen group.- um.1. C83218331C8333 1 and Alcoxi C83218833123；R8308；]1. Apartment No. C83218331；Alcoxi C8321883318323237A,Halogen.- um.- Oh,- No. 8313； No. 830404；R8308；]Each R8308； (758080) is selected independently from the C8321833183323 rental unit；Alcoxi C8321883318323237A,Halogen.- um.- Oh Y-NR8313； R830404；R83099 is hydrogen.1.C832183313523O-(Ch.8322296)； Or1；R8310 is hydrogen.1. Apartment No. C83218331；- (CH832226) 7496； (OR1,Cyoquilo C8323833183277o is heterosexual.A. Each group rents C8321A-8331832323；- (CH832226) 7496； (OR1,Cyoquilo C83238C83318327；A. One or two independent substitutes of C8321833123 asphalt group can be selected to replace isocyclopropyl.Alcoxi C8321883318323237A,Halogen.- Ch83228oh,- Cooh Y-Coch 8323；R8311811 is hydrogen or C832131 and R831222 ES-Y-Z；Or when R3 is - Conr8311； R831222,R831181 and R831222, together with the associated nitrogen, form an abiotic cyclopentanediol.In this case, one or two independent C83218331832323 tar groups can be selected to replace the isopropyl group.Halogen.- NH832222,- CH83222NH8
