Johnson, Keryn Dallas,May, Barnaby Charles Hough,Ward, Brian Roderick
申请号:
AU2009277252
公开号:
AU2009277252B2
申请日:
2009.07.30
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
The present invention pertains to the development of Extracellular Matrix (ECM) scaffolds derived from the forestomach of a ruminant. Such scaffolds are useful in many clinical and therapeutic applications, including wound repair, tissue regeneration, and breast reconstruction. In addition, the present invention features methods of isolating ECM scaffolds from mammalian organs, including but not limited to the ruminant forestomach. Such methods include the generation of a transmural osmotic flow between two sides of the tissue. The invention further features laminated ECM scaffolds containing a polymer positioned between individual EMC sheets. The polymer may optionally contain bioactive molecules to enhance the functionality of the scaffold.