Wim Annaert,Ragna Sannerud,Katrijn Coen,Bart De Strooper
申请号：
US13512851
公开号：
US20120276076A1
申请日:
2010.12.06
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention relates to the field of disorders of the peripheral or central nervous system, in particular, Alzheimers disease, and the prevention and/or treatment thereof. In particular, the invention relates to ARF6 and/or ARF6 effector proteins as new targets in Alzheimers disease, and based thereon, screening methods for compounds that reduce amyloid beta peptide formation in mammalian cells by affecting ARF6-mediated endosomal sorting.
