POMPER, MARTIN G.,MEASE, RONNIE C.,KUMAR, VIVEK,RAY, SANGEETA,ZALUTSKY, MICHAEL,VAIDYANATHAN, GANESAN
申请号:
CA3090495
公开号:
CA3090495A1
申请日:
2019.02.06
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
Small molecule radiohalogenated PSMA inhibitors and metal complexes thereof and their use in radioimaging and radiotherapy for treating PSMA-related diseases, including prostate cancer, are disclosed. The combination of small molecule radiohalogenated PSMA inhibitors with a competitive PSMA ligand for reducing offtarget accumulation of the radiohalogenated PSMA inhibitor also is disclosed.