Riddhi Shah,Fujian Qu,Yelena Nabutovsky,Dan E. Gutfinger,Ryan Rooke,Alex Soriano
申请号：
US13007364
公开号：
US20120184859A1
申请日:
2011.01.14
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Various techniques are provided for assessing the reliability of left atrial pressure (LAP) estimates made by an implantable medical device based on impedance values or related electrical values. In one example, various cardioelectric and cardiomechanical parameters are used to corroborate LAP estimation in circumstances where the LAP estimates deviate from an acceptable, satisfactory or otherwise healthy range. The cardioelectric parameters include, e.g.: ST elevation heart rate (HR) heart rate variability (HRV) T-wave alternans (TWA) QRS waveform parameters P-wave duration evoked response (ER) parameters and intrinsic PV/AV/VV conduction delays. The cardiomechanical parameters include, e.g.: heart rate turbulence (HRT) cardiogenic impedance signals heart sounds and non-LAP blood pressure measurements, such as aortic pressure measurements. The device compares the cardioelectric and cardiomechanical parameters against corresponding baseline values to determine whether variations in the parameters corroborate the LAP estimates. If not, the LAP estimates are selectively cancelled or suspended, or the overall procedure is re-calibrated.
