Method and kit for detecting phospholipid hydroperoxide dependent cell death, inhibitor of phospholipid hydroperoxide dependent cell death, and prevention or treatment of cardiac insufficiency or arrhythmia sudden death

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专利权人:

学校法人北里研究所

发明人:

今井 浩孝

申请号：

JP2018042365

公开号：

JP6646303B2

申请日:

2018.03.08

申请国别(地区):

JP

年份:

2020

代理人:

摘要：

PROBLEM TO BE SOLVED: To provide a method, kit, proteins and nucleic acid for detecting phospholipid hydroperoxide dependent cell death, and a prophylactic or therapeutic agent for diseases related to phospholipid hydroperoxide dependent cell death by identifying the factors involved in the pathway of cell death by PHGPx deficiency.SOLUTION: The method for detecting phospholipid hydroperoxide dependent cell death, comprises the step of detecting generation of phospholipid hydroperoxide and activation of Cdadc1 homolog in a cell sample.SELECTED DRAWING: Figure 27

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