The effect of 12 weeks of euenergetic high-protein diet in regulating appetite and body composition of women with normal-weight obesity: a randomised controlled trial

• 全文链接
• 请求原文

作   者：

Haghighat, Neda;  Ashtary-Larky, Damoon;  Bagheri, Reza;  Mahmoodi, Marzieh;  Rajaei, Majdadin;  Alipour, Meysam;  Kooti, Wesam;  Aghamohammdi, Vahideh;  Wong, Alexei; 

作者机构：

Khalkhal Univ Med Sci;  Dept Clin Biochem;  Dept Hlth & Human Performance;  Laparascopy Res Ctr;  Ahvaz Jundishapur Univ Med Sci;  Shiraz 7134814336;  Res Inst Hlth Dev;  Lung Dis & Allergy Res Ctr Res;  Sch Nutr & Food Sci;  Ahwaz 6135715794;  Dept Exercise Physiol;  Esfahan 8174673441;  Dept Nutr;  Shiraz Univ Med Sci;  Sch Med;  Khalkhal 5681761351;  Arlington;  Kurdistan Univ Med Sci;  Nutr Res Ctr;  Dept Radiotherapy & Oncol;  Iran;  Sanandaj 13446666147;  Univ Isfahan;  VA 22207 USA;  Marymount Univ; 

关键词：

Obesity;  Normal-weight obesity;  Diet;  High-protein diet;  Weight loss;  Body composition; 

期刊名称：

The British Journal of Nutrition

i s s n：

0007-1145

年卷期：

2020 年 124 卷 10 期

页   码：

1044-1051

页   码：

摘   要：

Normal-weight obesity (NWO) syndrome is associated with metabolic diseases. The present study aimed to investigate the effects of 12 weeks of a high-protein (HP)v. a standard protein (SP) diet on appetite, anthropometry and body composition in NWO women. In this clinical trial, fifty NWO women were randomly allocated to HP (n25) or SP (n25) diet groups. Women in the HP and SP groups consumed 25 and 15 % of their total energy intake from protein for 12 weeks. Weight, fat mass (FM), lean body mass (LBM), waist circumference (WC) and appetite were evaluated at baseline and following their 3-month intervention. After 12 weeks, the LBM was higher in HP compared with no significant changes in the SP group (mean between-group difference = 1 center dot 5 kg; 95 % CI 3 center dot 1, 0 center dot 01; effect size (d) = 0 center dot 4). Furthermore, the HP group had lower FM (mean between-group difference -1 center dot 1 kg; 95 % CI 1, -3 center dot 3;d= -0 center dot 2), body fat percentage (BFP) (mean between-group difference -2 %; 95 % CI 0 center dot 7, -5 center dot 2;d= -0 center dot 3) and WC (mean between-group difference -1 center dot 4 cm; 95 % CI 0 center dot 6, -3 center dot 6;d= -0 center dot 2) at the end of the study in comparison with the SP group. In both groups, weight and appetite were unchanged over time without significant differences between groups. Twelve weeks of euenergetic diets with different dietary protein contents resulted in no significant weight loss in women with NWO. However, an HP diet significantly improved body composition (LBM, FM, BFP and WC) in this population.