Gradient supercritical fluid chromatography coupled to mass spectrometry with a gradient flow of make-up solvent for enantioseparation of cathinones

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作   者：

Kolderova, Natalie;  Jurasek, Bronislav;  Kuchar, Martin;  Lindner, Wolfgang;  Kohout, Michal; 

作者机构：

Czech Republic;  Dept Organ Chem;  Ziegelofengasse 37;  Lindner Consulting GmbH;  Prague 16628;  Tech 3;  A-3400 Klosterneuburg;  Tech 5;  Austria;  Univ Chem & Technol;  Forens Lab Biol Act Subst; 

关键词：

Cathinones;  Chiral separation;  Make-up solvent gradient;  Chiral zwitterion ion exchanger;  Mass spectrometry;  Supercritical fluid chromatography; 

期刊名称：

Journal of chromatography, A: Including electrophoresis and other separation methods

i s s n：

0021-9673

年卷期：

2020 年 1625 卷

页   码：

摘   要：

In the past two decades, supercritical fluid chromatography has evolved from a niche application to a comprehensive technology and a fully-fledged alternative to conventional high-performance liquid chromatography.