Restless Genital Syndrome Induced by Milnacipran

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作   者：

Miyake, Keita;  Takaki, Manabu;  Sakamoto, Shinji;  Kawada, Kiyohiro;  Inoue, Shinichiro;  Yamada, Norihito; 

作者机构：

Grad Sch Med Dent & Pharmaceut Sci;  Japan;  Dept Neuropsychiat;  Okayama;  Okayama Univ; 

关键词：

milnacipran;  restless legs syndrome;  gabapentin enacarbil;  depression;  restless genital syndrome; 

期刊名称：

Clinical neuropharmacology

i s s n：

0362-5664

年卷期：

2018 年 41 卷 3 期

页   码：

109-110

页   码：

摘   要：

Objectives Restless genital syndrome (RGS) includes discomfort, pain, numbness, vibration, restlessness, or a burning sensation involving the vagina, perineum, pelvis, penis, and proximal portion of the lower limbs in patients. The RGS has been sometimes reported in Parkinson disease. In patients without Parkinson disease, RGS is also known as persistent genital arousal disorder (PSAS), which includes uncontrollable genital arousal, with or without orgasm or genital engorgement, unrelated to sexual desire. Although withdrawal from selective serotonin reuptake inhibitors antidepressants is reported to induce PSAS, there is no report of RGS or PSAS induced by antidepressants.