Automated resolution of dichlorvos and methylparaoxon pesticide mixtures employing a Flow Injection system with an inhibition electronic tongue

• 全文链接
• 请求原文

作   者：

Valdes-Ramirez G;  Gutierrez M;  del Valle M;  Ramirez-Silva MT;  Fournier D;  Marty JL; 

作者机构：

DF;  M] Univ Autonoma Barcelona;  MT] Univ Autonoma Metropolitana Iztapalapa;  Dept Quim;  Mexico City 09340;  Mexico;  G;  Spain;  Marty;  Dept Chem;  Bellaterra 08193;  [Valdes-Ramirez;  Ramirez-Silva;  M;  del Valle;  IMAGES EA 4218;  Sensors & Biosensors Grp;  JL] UPVD;  France;  Ctr Phytopharm;  [Gutierrez;  F-66860 Perpignan; 

关键词：

Bioelectronic tongue;  Flow Injection Analysis;  IONS;  IMMOBILIZED ACETYLCHOLINESTERASE;  Acetylcholinesterase;  SENSORS;  ARTIFICIAL NEURAL-NETWORKS;  Methylparaoxon;  PARAOXON;  CHEMOMETRICS;  Artificial Neural Networks;  ORGANIC-SOLVENTS;  Dichlorvos;  ORGANOPHOSPHATE PESTICIDES;  BIOSENSOR;  SAMPLES; 

期刊名称：

Biosensors & Bioelectronics: The International Journal for the Professional Involved with Research, Technology and Applications of Biosensers and Related Devices

i s s n：

0956-5663

年卷期：

2009 年 24 卷 5 期

页   码：

1103-1108

页   码：

摘   要：

An amperometric biosensor array has been developed to resolve pesticide mixtures of dichlorvos and methylparaoxon. The biosensor array has been used in a Flow Injection system, in order to operate automatically the inhibition procedure. The sensors used were three screen-printed amperometric biosensors that incorporated three different acetylcholinesterase enzymes: the wild type from Electric eel and two different genetically modified enzymes, B1 and B394 mutants, from Drosophila melanogaster. The inhibition response triplet was modelled using an Artificial Neural Network which was trained with mixture solutions that contain dichlorvos from 10(-4) to 0.1 mu M and methylparaoxon from 0.001 to 2.5 mu M. This system can be considered an inhibition electronic tongue. (c) 2008 Elsevier B.V. All rights reserved.