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Data from: Development of an adrenocortical cancer humanized mouse model to characterize anti-PD1 effects on tumor microenvironment
负责人:
关键词:
Adrenocortical carcinoma;immunotherapy;humanized mouse PDX model;anti-PD-1
DOI:
doi:10.5061/dryad.f8q4350
摘要:
of metastasis. Pre-treatment analysis of the patient’s metastatic liver lesion demonstrated abundant intra-tumoral CD8+ T cells by immunohistochemistry
Data from: Comparative genotoxicity of TEMPO and three of its derivatives in mouse lymphoma cells
负责人:
关键词:
DOI:
doi:10.5061/dryad.v1955
摘要:
loci (i.e., chromosome damage <31 Mbp). These results suggest that TEMPO and its three derivatives are cytotoxic and mutagenic in mouse lymphoma cells
Data from: The loss of hemoglobin and myoglobin does not minimize oxidative stress in Antarctic icefishes
负责人:
关键词:
Notothenia coriiceps;Pseudochaenichthys georgianus;Champsocephalus gunnari;Chaenocephalus aceratus;Antarctic fish;hemoglobin;myoglobin;Oxidative stress;Gobionotothen gibberifrons;Chionodraco rastrospinosus
DOI:
doi:10.5061/dryad.5228g
摘要:
stress. Levels and activity of pro-oxidants, small-molecule and enzymatic antioxidants, and levels of oxidized lipids and proteins in liver, oxidative
Data from: Fine mapping quanitative trait loci affecting murine external ear tissue regeneration in the LG/J by SM/J advanced intercross line
负责人:
关键词:
tissue regeneration;wound healing;SM\/J;LG\/J;QTL
DOI:
doi:10.5061/dryad.vc473
摘要:
External ear hole closure in LG/J mice represents a model of regenerative response. It is accompanied by the formation of a blastema-like structure
Data from: Dissecting molecular stress networks: identifying nodes of divergence between life-history phenotypes
负责人:
关键词:
Thamnophis elegans;Life History Evolution;Transcriptomics;Phenotypic Plasticity;Comparative Physiology;Ecological Genetics;Adaptation
DOI:
doi:10.5061/dryad.sb30r
摘要:
levels of reactive oxygen species (superoxide, H2O2); liver gene expression of GPX1 and erythrocyte DNA damage. Additionally, allele frequencies for SOD2
Data from: Influences of sodium and glycosaminoglycans on skin edema and the potential for ulceration: a finite element approach
负责人:
关键词:
sodium;Edema;inflammation;Finite Element;GAGs;venous ulcers;stasis ulcers
DOI:
doi:10.5061/dryad.8tp4q6d
摘要:
within two years. It is commonly accepted that venous ulcers are caused by the insufficiency of the calf muscle pump, leading to blood pooling in the lower
Data from: A survey of risk tolerance to multiple sclerosis therapies
负责人:
关键词:
decision making;NARCOMS Registry;: Multiple Sclerosis;disease modifying therapy;Risk Tolerance
DOI:
doi:10.5061/dryad.tg142pt
摘要:
, kidney injury, thyroid injury, liver injury, and PML. Results: Both progressive multifocal leukoencephalopathy (PML) and kidney injury had lowest
Data from: The core planar cell polarity gene, Vangl2, directs adult corneal epithelial cell alignment and migration
负责人:
关键词:
Vangl2;cornea;Planar Cell Polarity;epithelium
DOI:
doi:10.5061/dryad.1qh4c
摘要:
squamous epithelium on the outer surface of the vertebrate eye. Expression of multiple core PCP genes was demonstrated in the adult corneal epithelium. PCP components
Data from: Thyroid hormone protects primary cortical neurons exposed to hypoxia by reducing DNA methylation and apoptosis
负责人:
关键词:
hypoxia;Tet;Mus musculus;KLF9;Thyroid hormone;5-hydroxymethylcytosine (5hmc);DNA methyltransferase (Dnmt)
DOI:
doi:10.5061/dryad.7b980d8
摘要:
, administered shortly after injury, has been shown to promote neural protection in rodent TBI models. The mechanism of TH protection, however, is not establi
Data from: Elovanoids counteract oligomeric ?-Amyloid-induced gene expression and protect photoreceptors
负责人:
关键词:
DOI:
doi:10.5061/dryad.59zw3r233
摘要:
) and elovanoids (ELVs). To mimic an inflammatory milieu in wild-type (WT) mouse, we triggered retinal pigment epithelium (RPE) damage/PRC death by subretinally

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