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Data from: Structural consequence of the most frequently recurring cancer-associated substitution in DNA polymerase ?
- 负责人：
- DOI：
- doi:10.5061/dryad.1sb340g
- 摘要：
- not observed with the exonuclease-inactive Pol ??D290A,E292A variant lacking the catalytic residues. These results reveal a distinct mechanism of exonuclease
Private Environmental Protection 1987
- 负责人：
- EMNID, Bielefeld
- DOI：
- doi:10.4232/1.1721
- 摘要：
- for low-emission cars; interest in equipping personal car with a catalytic converter; consideration of tax advantages and additional costs of instal
Data from: Domain loss facilitates accelerated evolution and neofunctionalization of duplicate snake venom metalloproteinase toxin genes
- 负责人：
- 关键词：
- domain loss;gene duplication;metalloproteinase;Serpentes;positive selection;molecular evolution
- DOI：
- doi:10.5061/dryad.8979
- 摘要：
- gene families evolve and detail how the loss of domain structures can catalyse the accelerated evolution of novel gene paralogues. The ensuing generation of differing
Data from: Ecological opportunity alters the timing and shape of adaptive radiation
- 负责人：
- DOI：
- doi:10.5061/dryad.nh539
- 摘要：
- The uneven distribution of diversity is a conspicuous phenomenon across the tree of life. Ecological opportunity is a prominent catalyst
Data from: Alcohol discrimination and preferences in two species of nectar-feeding primate
- 负责人：
- DOI：
- doi:10.5061/dryad.831g4
- 摘要：
- to catabolize alcohol during digestion. The mutation increases catalytic efficiency 40-fold and may confer a selective advantage to aye-ayes that consume
Data from: Identification and evaluation of novel acetolactate synthase inhibitors as antifungal agents
- 负责人：
- DOI：
- doi:10.5061/dryad.qb753
- 摘要：
- nt clones with 3 different mutations in the catalytic subunit of acetolactate synthase that also conferred cross-resistance to established Ilv2p inhibitors
Data from: Modelling dynamics in protein crystal structures by ensemble refinement
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.5n01h
- 摘要：
- binding, enzyme activity and protomer assembly. Order–disorder changes in HIV protease indicate a mechanism of entropy compensation for ordering the catalytic residues upon
Data from: Extensive horizontal gene transfer, duplication, and loss of chlorophyll synthesis genes in the algae
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.3ss6p
- 摘要：
- Background: Two non-homologous, isofunctional enzymes catalyze the penultimate step of chlorophyll a synthesis in oxygenic photosynthetic organisms
Data from: Structure-based network analysis of activation mechanisms in the ErbB family of receptor tyrosine kinases: the regulatory spine residues
- 负责人：
- 关键词：
- protein kinases;protein structure network analysis;structural stability;force constant analysis
- DOI：
- doi:10.5061/dryad.qj597
- 摘要：
- of the conserved His-Arg-Asp (HRD) motif in the catalytic loop and the Asp-Phe-Gly (DFG) motif as key mediators of structural stability and allosteric communicat
Data from: Forward genetic screening for regulators involved in cholesterol synthesis using validation-based insertional mutagenesis
- 负责人：
- DOI：
- doi:10.5061/dryad.p100g
- 摘要：
- cleavage-activating protein (SCAP). Besides, one SR-12813 resistant mutant was identified to contain a truncated COOH-terminal catalytic
