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Data from: Degenerate adaptor sequences for detecting PCR duplicates in reduced representation sequencing data improve genotype calling accuracy
- 负责人:
- DOI:
- doi:10.5061/dryad.34dt1
- 摘要:
- ng double-digest libraries of ants (Wasmannia auropunctata) and yeast (Saccharomyces cerevisiae) with known genotypes, producing modest though statistically
Data from: Aneuploidy causes non-genetic individuality
- 负责人:
- DOI:
- doi:10.5061/dryad.30mv0
- 摘要:
- Phenotypic variability is a hallmark of diseases involving chromosome gains and losses, such as Down syndrome and cancer. Allelic variances ha
Data from: Too much of a good thing: The unique and repeated paths toward copper adaptation
- 负责人:
- DOI:
- doi:10.5061/dryad.5gp25
- 摘要:
- r ancestral environment. Here, we report a short-term evolutionary study of Saccharomyces cerevisiae exposed to levels of copper sulfate that are inhibitory
Data from: Live-cell single particle imaging reveals the role of RNA polymerase II in histone H2A.Z eviction
- 负责人:
- DOI:
- doi:10.5061/dryad.43cp80c
- 摘要:
- is deposited by the SWR1 chromatin remodeler and evicted by unclear mechanisms. We tracked H2A.Z in living yeast at single-molecule resolution, and found tha
Data from: The effect of hybrid transgression on environmental tolerance in experimental yeast crosses
- 负责人:
- DOI:
- doi:10.5061/dryad.83qh4
- 摘要:
- h Saccharomyces cerevisiae and S. paradoxus) with different genetic and phenotypic divergence. We compared the ability of hybrids and parents to colonize seven types
Data from: Dynamic relocalization of replication origins by Fkh1 requires execution of DDK function and Cdc45 loading at origins
- 负责人:
- DOI:
- doi:10.5061/dryad.7bm444s
- 摘要:
- e dynamic structures are poorly understood. In S. cerevisiae, replication origins exhibit characteristic subnuclear localizations prior to S phase that anticipate thei
Data from: Essential gene disruptions reveal complex relationships between phenotypic robustness, pleiotropy, and fitness
- 负责人:
- DOI:
- doi:10.5061/dryad.ft7dj
- 摘要:
- ed to reduce expression. Using high?throughput microscopy and image analysis, we have characterized a large number of morphological phenotypes, and their associa
Data from: Extensive heterosis in growth of yeast hybrids is explained by a combination of genetic models
- 负责人:
- DOI:
- doi:10.5061/dryad.4j07v
- 摘要:
- parental yeast strains to form 120 yeast hybrids, and measured their growth rates under five environmental conditions. A considerable amount of dominant genetic varia
Data from: Loss of growth homeostasis by genetic decoupling of cell division from biomass growth: implication for size control mechanisms
- 负责人:
- DOI:
- doi:10.5061/dryad.r4n35
- 摘要:
- Growing cells adjust their division time with biomass accumulation to maintain growth homeostasis. Size control mechanisms, such as the si
Data from: High throughput functional genomics identifies modulators of TCE metabolite genotoxicity and candidate susceptibility genes
- 负责人:
- DOI:
- doi:10.5061/dryad.p8k18
- 摘要:
- carcinogenesis associated with TCE exposure, yet the toxicity mechanisms of these metabolites and their contribution to cancer and other adverse effects remain