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Data from: Male-biased fitness effects of spontaneous mutations in Drosophila melanogaster
- 负责人：
- DOI：
- doi:10.5061/dryad.368nr
- 摘要：
- of mutation accumulation lines of Drosophila melanogaster, we found that mutations were deleterious in both sexes and had larger effects on fitness in males than in females
Data from: The fitness cost of mismatch repair mutators in Saccharomyces cerevisiae: partitioning the mutational load
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.4b10j7q
- 摘要：
- Mutational load is the depression in a population's mean fitness that results from the continual influx of deleterious mutations. Here, we direct
Data from: Evolution of fitness trade-offs in locally adapted populations of Pseudomonas fluorescens
- 负责人：
- DOI：
- doi:10.5061/dryad.254s7
- 摘要：
- on on three different carbon resources. We measured the fitness effects of mutations that arose during selection in that environment and in alternati
Data from: Experiments on the role of deleterious mutations as stepping stones in adaptive evolution
- 负责人：
- DOI：
- doi:10.5061/dryad.4hp5n
- 摘要：
- fitness levels were achieved over the long term in the control populations because some of the deleterious mutations served as stepping stones across other
Data from: Stabilizing selection, mutational bias and the evolution of sex
- 负责人：
- DOI：
- doi:10.5061/dryad.50q65s0
- 摘要：
- the mean fitness of asexual populations compared with sexual ones in regimes where mutations have weak to moderate fitness effects. Indeed, mutation
Data from: Evolution of haploid–diploid life cycles when haploid and diploid fitnesses are not equal
- 负责人：
- 关键词：
- life cycle evolution;alternation of generations;modifier model;diplohaplontic;multilocus simulations
- DOI：
- doi:10.5061/dryad.3sr84
- 摘要：
- w mutations are masked. Life-cycle evolution can be affected by intrinsic fitness differences between phases, the masking of mutations, or a combination of bot
Data from: On the (un)predictability of a large intragenic fitness landscape
- 负责人：
- DOI：
- doi:10.5061/dryad.th0rj
- 摘要：
- combined with next-generation sequencing (NGS) methods enable accurate and extensive studies of the fitness effects of mutations, allowing us to tes
Data from: Epistasis buffers the fitness effects of rifampicin-resistance mutations in Pseudomonas aeruginosa
- 负责人：
- DOI：
- doi:10.5061/dryad.8858
- 摘要：
- . First, we show that epistasis between rifampicin-resistance mutations tends to be antagonistic: the fitness effect of having two mutations is gene
Data from: Mapping the fitness landscape of gene expression uncovers the cause of antagonism and sign epistasis between adaptive mutations
- 负责人：
- 关键词：
- Experimental evolution;epistasis;Adaptation;fitness landscape;Metabolism;Methylobacterium extorquens
- DOI：
- doi:10.5061/dryad.8hb23
- 摘要：
- bolism of Methylobacterium extorquens to uncover the fitness landscape defined by gene expression levels. We found strong antagonism and sign epistasis between these beneficial mutations
Data from: Sex and genotype effects on nutrient-dependent fitness landscapes in Drosophila melanogaster
- 负责人：
- DOI：
- doi:10.5061/dryad.js480
- 摘要：
- on and metabolic fitness effects by screening male and female fitness of thirty D. melanogaster genotypes across four protein-to-carbohydrate ratios. In additi
