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Data from: The role of the environment in the evolution of tolerance and resistance to a pathogen
- 负责人:
- DOI:
- doi:10.5061/dryad.r1s5d
- 摘要:
- Defense against parasites can be divided into resistance, which limits parasite burden, and tolerance, which reduces pathogenesis at a give
Data from: Whole genome sequencing shows sleeping sickness relapse is due to parasite regrowth and not reinfection
- 负责人:
- DOI:
- doi:10.5061/dryad.d58b8
- 摘要:
- d whole genome sequencing to investigate whether these patients were infected with a new strain, or if the original strain had regrown to pathogenic levels
Data from: CSF1R-related leukoencephalopathy: a major player in primary microgliopathies
- 负责人:
- 关键词:
- DOI:
- doi:10.5061/dryad.498j63f
- 摘要:
- have a pivotal and primary role in pathogenesis. In this review, we address the current knowledge of CSF1R-related leukoencephalopathy and discuss
Data from: Efferocytosis and extrusion of leukocytes determine the progression of early mycobacterial pathogenesis
- 负责人:
- DOI:
- doi:10.5061/dryad.08803
- 摘要:
- Macrophages and neutrophils are the first responders to invading pathogens and contribute strongly to the host defense ag
Data from: Macrophage migration inhibitory factor is involved in ectopic endometrial tissue growth and peritoneal-endometrial tissue interaction
- 负责人:
- DOI:
- doi:10.5061/dryad.5q8ht
- 摘要:
- Pelvic inflammation is a hallmark of endometriosis pathogenesis and a major cause of the disease's symptoms. Abnormal immune and inflammatory changes
Data from: Selected HLA-B allotypes are resistant to inhibition or deficiency of the transporter associated with antigen processing (TAP)
- 负责人:
- 关键词:
- DOI:
- doi:10.5061/dryad.m4862mk
- 摘要:
- ways, thereby conferring resistance to pathogen-derived inhibitors of TAP. To broadly assess TAP-independent expression within the HLA-B locus
Data from: Immunogenetic response of the bananaquit in the face of malarial parasites
- 负责人:
- DOI:
- doi:10.5061/dryad.f47d293
- 摘要:
- t display antigens as part of the vertebrate adaptive immune system. Thus, both gene families are under selection pressure from pathogens. The bananaquit
Data from: Immune response costs are associated with changes in resource acquisition and not resource reallocation
- 负责人:
- DOI:
- doi:10.5061/dryad.5b14n
- 摘要:
- ulted from immune system activation not pathogenesis. 4. These costs of immune activation are significant for individuals that successfully resis
Data from: Genome-wide sensitivity analysis of the microsymbiont Sinorhizobium meliloti to symbiotically important, defensin-like host peptides
- 负责人:
- DOI:
- doi:10.5061/dryad.32152
- 摘要:
- ng transposon mutagenesis followed by high-throughput sequencing (Tn-seq) to identify S. meliloti genes and pathways that increase or decrease bacterial competitiveness duri
Data from: Parasite-mediated selection drives an immunogenetic tradeoff in plains zebras (Equus quagga)
- 负责人:
- DOI:
- doi:10.5061/dryad.p083b
- 摘要:
- Pathogen evasion of the host immune system is a key force driving extreme polymorphism in genes of the major histocompatibility complex (MHC). Alt