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Data from: The Caenorhabditis elegans Myc-Mondo/Mad complexes integrate diverse longevity signals
负责人:
关键词:
mondo;transcription;max;caloric restriction;transcription factors;mad;Caenorhabditis elegans;insulin signaling;Myc;nutrient sensing;mlx;Dietary restriction;genetics of aging
DOI:
doi:10.5061/dryad.pj0p3
摘要:
and found significant overlap in genomic DNA binding between the major effectors of ILS (DAF-16/FoxO), DR (PHA-4/FoxA), and Myc family (MDL-1/Mad/Mxd) at common
Data supporting Cachat et al. (2017): "Synthetic self-patterning and morphogenesis in mammalian cells: a proof-of-concept step towards synthetic tissue development"
负责人:
University Of Edinburgh;;University Of Edinburgh
关键词:
synthetic morphology patterning apoptosis self-organisation synthetic tissue Biological Sciences::Developmental Biology
DOI:
doi:10.7488/ds/2060
摘要:
device demonstrates and validates the idea of coupling synthetic biological morphogenetic effectors to synthetic biological patterning devices. It opens
Data from: The induction of the fibroblast extracellular senescence metabolome is a dynamic process
负责人:
关键词:
metabolomics;senescence;Ageing;Homo Sapiens;p16INK4A;Holocene
DOI:
doi:10.5061/dryad.45747rs
摘要:
evealed its independence from the senescence effector p16INK4A. These data will aid our understanding of metabolic signatures of ageing and their relationship
Data from: The battle of the sexes over seed size: support for both kinship genomic imprinting and interlocus contest evolution
负责人:
关键词:
Mating Systems;Evolution: developmental;Genetics: population;Genetics: quantitative;conflict;development;Conflict: sexual;Sex: allocation;Holocene;Genetics: evolutionary;Conflict: parent\/offsprint;Arabidopsis lyrata
DOI:
doi:10.5061/dryad.rv313
摘要:
of this conflict include the kinship theory of genomic imprinting (parent-of-origin-specific expression of maternal-care effectors) and interlocus conflict evolution
Data from: Common internal allosteric network links anesthetic binding sites in a pentameric ligand-gated ion channel
负责人:
关键词:
ion channel;propofol;molecular dynamics;GLIC;allostery
DOI:
doi:10.5061/dryad.sp025
摘要:
effector sites necessary for conformational change. Overall, the results suggest that the same allosteric network may underlie the actions of var
Data from: Cytoskeletal stability and metabolic alterations in primary human macrophages in long-term microgravity
负责人:
关键词:
microgravity;Innate immunity;macrophage;space;space flight
DOI:
doi:10.5061/dryad.576m2
摘要:
investigated for the first time microgravity-associated long-term alterations in primary human macrophages, one of the most important effector
Data from: A quantitative proteomic analysis of cofilin phosphorylation in myeloid cells and its modulation using the LIM kinase inhibitor Pyr1
负责人:
关键词:
Lim kinases;leukemia;Mus musculus;cofilin;proteomics;Homo Sapiens;phosphorylation
DOI:
doi:10.5061/dryad.4n5929c
摘要:
LIM kinases are located at a strategic crossroad, downstream of several signaling pathways and upstream of effectors such as microtubules

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