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Data from: Genomic changes following the reversal of a Y chromosome to an autosome in Drosophila pseudoobscura
- 负责人：
- 关键词：
- SMRT sequencing;Robertsonian translocation;Y chromosome;dot chromosome;Drosophila pseudoobsucra
- DOI：
- doi:10.5061/dryad.rp949
- 摘要：
- in Drosophila pseudoobscura. The ancestral Y chromosome fused to a small autosome (the dot chromosome) approximately 10–15 Mya. We used single molecule real-time sequencing
Data from: High-throughput screening for ligands of the HEPN domain of sacsin
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.8f150
- 摘要：
- ogs revealed that the binding is primarily mediated by the phosphate groups of nucleotides. A high-throughput screen subsequently identified novel small molecule
Data from: Degenerate adaptor sequences for detecting PCR duplicates in reduced representation sequencing data improve genotype calling accuracy
- 负责人：
- DOI：
- doi:10.5061/dryad.34dt1
- 摘要：
- tic digestion and sequencing adaptor ligation. Amplification introduces duplicate reads into the data, which arise from the same template molecule and are statistical
LIM Domain Kinase 1 (LIMK1), Human Kinase Domain; A Target Enabling Package
- 负责人：
- Eidarus Salah;;Beltrami, Alessandra;;Apirat Chaikuad;;Hanke, Thomas;;Kashima, Risa;;Canning, Peter;;Knapp, Susanne Muller;;Knaus, Petra;;Hata, Akiko
- DOI：
- doi:10.5287/bodleian:zg5naqjyk
- 摘要：
- , as well as multiple assays for small molecule inhibitor screening. Finally, we identify a series of allosteric LIMK1 inhibitors with promising potency and selec
Data from: Global metabolic interaction network of the human gut microbiota for context-specific community-scale analysis
- 负责人：
- DOI：
- doi:10.5061/dryad.mc1j9
- 摘要：
- of ?570 microbial species and 3 human cell types metabolically interacting through >4,400 small-molecule transport and macromolecule degradation events
Data from: Genetic analyses in Lake Malawi cichlids identify new roles for Fgf signaling in scale shape variation
- 负责人：
- DOI：
- doi:10.5061/dryad.35cp405
- 摘要：
- target. Quantitative rtPCR and small molecule manipulation support a role for Fgf signaling in shaping cichlid scales. While Fgfs have pr
Data from: Characterization of advanced glycation end products and their receptor (RAGE) in an animal model of myocardial infarction
- 负责人：
- Andrades, Michael
- DOI：
- doi:10.5061/dryad.jt52151
- 摘要：
- to be associated with worse prognosis in patients. Despite the increasing importance of these molecules in the course of cardiac diseases, they have neve
Data from: Decrease in ribosomal RNA in Candida albicans induced by serum exposure
- 负责人：
- DOI：
- doi:10.5061/dryad.th09b
- 摘要：
- rease in a molecule so central to the yeast’s biology is of some importance, and further studies, such as its effect on protein metabolism, will be required to bet
Data from: Understanding genetic variation in in vivo tolerance to artesunate: implications for treatment efficacy and resistance monitoring
- 负责人：
- DOI：
- doi:10.5061/dryad.v244v
- 摘要：
- infections may signal developing resistance to treatment. In the absence of molecular markers for resistance, current efforts to monitor drug efficacy ar
Data from: A new subfamily LIP of the major intrinsic proteins
- 负责人：
- DOI：
- doi:10.5061/dryad.8f61v
- 摘要：
- ortant in cells and organisms because they allow for passive transmembrane transport of water and other small, uncharged polar molecules. Result
