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Data from: Analysis of VEGFA variants and changes in VEGF levels underscores the contribution of VEGF to polycystic ovary syndrome
- 负责人：
- DOI：
- doi:10.5061/dryad.nb1hc
- 摘要：
- and rs2010963, respectively. Increased fasting insulin and HOMA-IR, and bioactive testosterone were linked with rs3025020, while carriage of rs2010963
Data from: An exploratory association analysis of the insulin gene region with diabetes mellitus in two dog breeds
- 负责人：
- DOI：
- doi:10.5061/dryad.pnvx0k6hm
- 摘要：
- if the insulin (INS) gene is involved in the pathophysiology of diabetes in Samoyeds and Australian Terriers. It was hypothesized that the INS gene region prov
Data from: Experimentally reduced insulin/IGF-1 signalling in adulthood extends lifespan of parents and improves Darwinian fitness of their offspring
- 负责人：
- DOI：
- doi:10.5061/dryad.8d2t65n
- 摘要：
- g in adulthood can simultaneously postpone ageing and increase Darwinian fitness. Here we show that reducing evolutionarily conserved insulin/IGF-1 nutrient
Data from: Monarch butterflies use an environmentally sensitive, internal timer to control overwintering dynamics
- 负责人：
- DOI：
- doi:10.5061/dryad.fd517kq
- 摘要：
- e implicated to be the proximate timing mechanism. Ecdysteroid, JH, and insulin/insulin-like peptide (IIS) signaling are major targets of the diapause program
Data from: The Drosophila HNF4 nuclear receptor promotes glucose-stimulated insulin secretion and mitochondrial function in adults
- 负责人：
- DOI：
- doi:10.5061/dryad.8h8q5
- 摘要：
- -onset hyperglycemia, glucose intolerance and impaired glucose-stimulated insulin secretion (GSIS). These defects are linked to a role for dHNF4
Data from: Relationship between high serum cystatin C levels and the risk of gestational diabetes mellitus
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.g0d1d
- 摘要：
- e compared. The serum CysC concentration was measured using immunoturbidimetry and the degree of insulin resistance was assessed by the homeostasis
Proinsulin-transferrin fusion protein as a liver targeting insulin therapeutic in Type 1 diabetes treatment
- 负责人：
- 关键词：
- Pharmaceutical Sciences proinsulin-transferrin fusion protein liver targeting diabetes long-acting insulin therapeutic
- DOI：
- doi:10.25549/usctheses-c40-250950
- 摘要：
- Long-acting insulin (INS) analogs have been used in the treatment of INS-deficient diabetes patients to meet INS needs between meal times and duri
Data from: PPAR? promotes diabetes-associated centrosome amplification via increasing the expression of SKA1 directly at the transcriptional level
- 负责人：
- DOI：
- doi:10.5061/dryad.hg225q3
- 摘要：
- and insulin, and ROCK1 and 14-3-3? are signal mediators. In this study, we further investigated the molecular mechanisms of the centrosome ampli
Data from: Expression and function of ATP-dependent potassium channels in zebrafish islet ?-cells
- 负责人：
- DOI：
- doi:10.5061/dryad.1v074
- 摘要：
- e essential for coupling glucose metabolism to insulin secretion. While orthologous genes for many components of metabolism–secretion coupling in mammals are pr
Data from: Longevity is determined by ETS transcription factors in multiple tissues and diverse species
- 负责人：
- DOI：
- doi:10.5061/dryad.5qv9750
- 摘要：
- criptional outcomes, which reveals a multi-tissue and multi-species role for an entire protein family: the E-twenty-six (ETS) TFs. In Drosophila, reduced insulin/IGF
