筛选
科学数据
统计数据
共检索到94条 ,权限内显示50条;
Data from: SNP genotyping identifies new signatures of selection in a deep sample of West African P. falciparum malaria parasites
- 负责人：
- DOI：
- doi:10.5061/dryad.731f5
- 摘要：
- h application of the iHS and REHH haplotype-based tests for positive selection, we found evidence of recent selective sweeps at a known drug resistance locus
Data from: High-throughput screening for ligands of the HEPN domain of sacsin
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.8f150
- 摘要：
- ligands of HEPN, providing new chemical probes for cell culture studies and drug development. Together, the results are consistent with the HEPN domain
Data from: Computational and experimental characterization of dVHL establish a Drosophila model of VHL syndrome
- 负责人：
- DOI：
- doi:10.5061/dryad.14pp7
- 摘要：
- Drosophila model is thus useful for studying the VHL syndrome, and for testing drug candidates to treat it.
Data from: Strain identification and quorum sensing inhibition characterization of marine-derived Rhizobium sp. NAO1
- 负责人：
- 关键词：
- Bacterium;Biofilm;open ocean;Mesozoic;Quorum-sensing inhibition;Rhizobium sp. NAO1;virulence factors
- DOI：
- doi:10.5061/dryad.27630
- 摘要：
- Rhizobium sp. NAO1 has the potential to serve as a QS inhibitor and may be a new microbial resource for drug development.
Data from: Mitochondrial dysfunction and infection generate immunity-fecundity tradeoffs in Drosophila
- 负责人：
- DOI：
- doi:10.5061/dryad.88mk4dh
- 摘要：
- for tradeoffs between immunity and fecundity. We found that an energetically-compromised genotype was relatively resistant to rapamycin – a drug that targets
The E3-ubiquitin ligase adaptor protein Skp1 is glycosylated by an evolutionarily conserved pathway that regulates protist growth and development.pdf
- 负责人：
- 关键词：
- 60102 Bioinformatics Cell Biology Microbiology Parasitology 60307 Host-Parasite Interactions 60502 Infectious Agents 110309 Infectious Diseases Pathology 60411 Population, Ecological and Evolutionary Genetics 60109 Proteomics and Intermolecular Interactions (excl. Medical Proteomics)
- DOI：
- doi:10.6084/m9.figshare.5505661.v1
- 摘要：
- to help develop it as a drug target for control of the pathogen, as the glycosyltransferases are absent from mammalian hosts.
Data from: Rapid assessment of conformational preferences in biaryl and aryl carbonyl fragments
- 负责人：
- DOI：
- doi:10.5061/dryad.fs6hq7b
- 摘要：
- in the process of drug design. With the ability to do so, one could address questions like: "How could we avoid planarity in a molecule?", "Will a molecule change
Data from: A highly sensitive LC-MS/MS method to determine novel Bruton's tyrosine kinase inhibitor spebrutinib: application to metabolic stability evaluation
- 负责人：
- DOI：
- doi:10.5061/dryad.5m09t8k
- 摘要：
- t SBT could be deliberately expelled from the body unlike other related tyrosine kinase inhibitors. So, drug plasma level and kidney function should
Data from: Enhancing the steroid sulfatase activity of the arylsulfatase from Pseudomonas aeruginosa
- 负责人：
- DOI：
- doi:10.5061/dryad.p5n151t
- 摘要：
- drug testing. Although the direct detection of steroid sulfates can be readily achieved using liquid chromatography-mass spectrometry, many analyti
Data from: Synthesis and characterization of silver nanoparticle-decorated cobalt nanocomposites (Co@AgNPs) and their density-dependent
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.0bk10qf
- 摘要：
- Magnetic cores loaded with metallic nanoparticles can be promising nano-carriers for successful drug delivery at infectious sites. We report
