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Data from: Temporal variation in antibiotic environments slows down resistance evolution in pathogenic Pseudomonas aeruginosa
- 负责人：
- DOI：
- doi:10.5061/dryad.c867b
- 摘要：
- Antibiotic resistance is a growing concern to public health. New treatment strategies may alleviate the situation by slowing down the evoluti
Data from: Linking system-wide impacts of RNA polymerase mutations to the fitness cost of rifampin resistance in Pseudomonas aeruginosa
- 负责人：
- DOI：
- doi:10.5061/dryad.vj35n
- 摘要：
- in the absence of antibiotics. Although the genetic basis of antibiotic resistance is well understood, the precise molecular mechanisms linking the genetic basis
Data from: Epistasis buffers the fitness effects of rifampicin-resistance mutations in Pseudomonas aeruginosa
- 负责人：
- DOI：
- doi:10.5061/dryad.8858
- 摘要：
- y be a key determinant of the cost of antibiotic resistance and compensatory adaptation in pathogen populations.
Data from: The fitness costs of antibiotic resistance mutations
- 负责人：
- DOI：
- doi:10.5061/dryad.5rc47
- 摘要：
- Antibiotic resistance is increasing in pathogenic microbial populations and is thus a major threat to public health. The fate of a resistance
Data from: Suppression of bacteriocin resistance using live, heterospecific competitors
- 负责人：
- DOI：
- doi:10.5061/dryad.11kf1ck
- 摘要：
- Rapidly spreading antibiotic resistance has led to the need for novel alternatives and sustainable strategies for antimicrobial use. Bacteriocins ar
Data from: Epistasis between antibiotic resistance mutations and genetic background shape the fitness effect of resistance across species
- 负责人：
- DOI：
- doi:10.5061/dryad.qn370
- 摘要：
- Antibiotic resistance often evolves by mutations at conserved sites in essential genes, resulting in parallel molecular evolution between divergent
Data from: Environmental pleiotropy and population demography direct adaptation under antibiotic selection
- 负责人：
- DOI：
- doi:10.5061/dryad.gp5g0j0
- 摘要：
- eract during antibiotic resistance evolution, a key example of evolutionary rescue fuelled by pre-existing mutations with pleiotropic fitness effects
Data from: Parasites and competitors suppress bacterial pathogen synergistically due to evolutionary trade-offs
- 负责人：
- DOI：
- doi:10.5061/dryad.m009s
- 摘要：
- to B. amyloliquefaciens antibiotics. While no evidence was found for pathogen resistance evolution to B. amyloliquefaciens antibiotics, the fitness cost of adaptati
Data from: Conjugation is necessary for a bacterial plasmid to survive under protozoan predation
- 负责人：
- DOI：
- doi:10.5061/dryad.t1b23
- 摘要：
- Horizontal gene transfer by conjugative plasmids plays a critical role in the evolution of antibiotic resistance. Interactions between bacteria
Data from: The SOS response increases bacterial fitness, but not evolvability, under a sublethal dose of antibiotic
- 负责人：
- DOI：
- doi:10.5061/dryad.rv766
- 摘要：
- . Continued exposure to ciprofloxacin results in the rapid evolution of increased fitness and antibiotic resistance, but we find no evidence that SOS
