Proinsulin-transferrin fusion protein as a liver targeting insulin therapeutic in Type 1 diabetes treatment

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Pharmaceutical Sciences proinsulin-transferrin fusion protein liver targeting diabetes long-acting insulin therapeutic

DOI：

doi:10.25549/usctheses-c40-250950

摘要：

the distribution or action of exogenous INS to more closely mimic physiological INS by demonstrating preferential hepatic action. However, specific to s.c-injec

Therapeutic potential of rhesus theta (θ) defensin-1 in cystic fibrosis airway infection and inflammation

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Clinical and Experimental Therapeutics cystic fibrosis infection inflammation preclinical drug development

DOI：

doi:10.25549/usctheses-c40-309144

摘要：

onsible for chronic lung infections in patients with CF is Pseudomonas aeruginosa. Based on published data demonstrating broad spectrum antimicrobial acti

Data from: Increasing procaspase 8 expression using repurposed drugs to induce HIV infected cell death in ex vivo patient cells

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Caspase 8;HIV

DOI：

doi:10.5061/dryad.19fg1

摘要：

ly to reduce cell-associated HIV DNA levels. We recently showed that following reactivation from latency, HIV infected cells generate the HIV specific cytotoxic protein Casp

Data from: The host response to the lung microbiome in Chromic Obstructive Pulmonary Disease

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bacteria;lung microbiome;COPD

DOI：

doi:10.5061/dryad.2p66n

摘要：

on, remodeling of the bronchiolar and alveolar tissue, and the infiltration of the tissue by CD4+ T cells. Specific OTUs were also associated with neutrophils