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Data from: Quantitative trait loci from the host genetic background modulate the durability of a resistance gene: a rational basis for susta
负责人:
关键词:
Genotype data;doubled haploid lines;Phenotype data;mapping population
DOI:
doi:10.5061/dryad.s4n76
摘要:
The combination of major resistance genes with quantitative resistance factors is hypothesized as a promising breeding strategy to preserve
Data from: Resource limitation prevents the emergence of drug resistance by intensifying within-host competition
负责人:
关键词:
Mus musculus;combination therapy;competition;Drug resistance;Plasmodium chabaudi
DOI:
doi:10.5061/dryad.v2q3v
摘要:
-resistant mutant grows to high densities, and so sickens the patient and spreads to new hosts, is determined by the competitive interactions it has with drug
Data from: Effects of genotype on rates of substitution during experimental evolution
负责人:
关键词:
Escherichia coli;molecular evolution;epistasis;Selection - Experimental;variation
DOI:
doi:10.5061/dryad.36td2
摘要:
the simultaneous fixation of several mutations, consistent with theoretical models of multiple mutation dynamics. Moreover, patterns of substitution were indicative
Data from: Quantitative genetic variance in experimental fly populations evolving with or without environmental heterogeneity
负责人:
关键词:
Genetic Variation;Selection - Experimental;quantitative genetics;drosophila melanogaster
DOI:
doi:10.5061/dryad.sr3g0
摘要:
environment is to the environment of past selection. Here we measure quantitative genetic variance for three traits important for fitness using replicated
Data from: Selection for novel metabolic capabilities in Salmonella enterica
负责人:
关键词:
carbon sources;Salmonella enterica;Experimental evolution;new metabolic functions;Novel phenotypes
DOI:
doi:10.5061/dryad.2qh4k34
摘要:
. We found mutants growing on 18 of these novel carbon sources, and identified the causal mutations that allowed growth for four of them. Mutations that relieve
Data from: No evidence for induction or selection of mutant sodium channel expression in the copepod Acartia husdsonica challenged
负责人:
关键词:
Acartia hudsonica;paralytic shellfish toxins;induction;sodium channel;Alexandrium fundyense;Alexandrium tamarense;Response to selection
DOI:
doi:10.5061/dryad.62v82
摘要:
Alexandrium fundyense; (2) in the absence of induction, selection exerted by toxic A. fundyense would favor copepods that predominantly express the mutant isoform
Data from: Epistasis buffers the fitness effects of rifampicin-resistance mutations in Pseudomonas aeruginosa
负责人:
关键词:
Mutations;Pseudomonas aeruginosa;epistasis
DOI:
doi:10.5061/dryad.8858
摘要:
, revealing a novel mechanism for compensatory adaptation. These results suggest that antagonistic epistasis between intragenic resistance mutations ma
Data from: Epistasis between antibiotic resistance mutations and genetic background shape the fitness effect of resistance across species
负责人:
关键词:
Experimental evolution;epistasis;antibiotic resistance;genetic background;fitness costs
DOI:
doi:10.5061/dryad.qn370
摘要:
Antibiotic resistance often evolves by mutations at conserved sites in essential genes, resulting in parallel molecular evolution between divergent
Data from: Novel conserved genotypes correspond to antibiotic resistance phenotypes of E. coli clinical isolates
负责人:
关键词:
Genome;clinical;bacterial;SNP;antibiotic resistance;Escherichia coli;diBayes;polymorphism
DOI:
doi:10.5061/dryad.r8q71
摘要:
strategies uncover novel mechanisms. To identify genomic variations associated with antibiotic resistance, we employed a modified genome-wide association study

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