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Data from: Evidence for an association between post-fledging dispersal and microsatellite multilocus heterozygosity in a large population of greater flamingos
负责人:
关键词:
HFC;microsatellite multilocus heterozygosity;Heterozygosity-fitness correlation;Phoenicopterus roseus;post-fledging dispersal;Holocene;greater ?amingos
DOI:
doi:10.5061/dryad.s1t53
摘要:
Dispersal can be divided into three stages: departure, transience and settlement. Despite the fact that theoretical studies have emphasized the importance of heterozygosity on dispersal strategies, empirical evidence of its effect on different stages of dispersal is lacking. Here, using multi-event capture-mark-recapture models, we show a negative association between microsatellite multilocus heterozygosity (MLH; 10 loci; n = 1023) and post-fledging dispersal propensity for greater flamingos, Phoenicopterus roseus, born in southern France. We propose that the negative effects of inbreeding depression affects competitive ability and therefore more homozygous individuals are more likely to disperse because they are less able to compete within the highly saturated natal site. Finally, a model with the effect of MLH on propensity of post-fledgling dispersers to disperse to the long-distance sites of Africa was equivalent to the null model, suggesting that MLH had low to no effect on dispersal distance. Variations in individual genetic quality thus result in context-dependent heterogeneity in dispersal strategies at each stage of dispersal. Our results have important implications on fitness since sites visited early in life are known to influence site selection later on in life and future survival.
Data from: Sexual selection on male body size, genital length and heterozygosity: consistency across habitats and social settings
负责人:
Head, Megan
关键词:
HFC Body size Environmental heterogeneity poeciliid reproductive success
DOI:
doi:10.5061/dryad.93351
摘要:
1. Spatial and temporal variation in environmental factors and the social setting can help to maintain genetic variation in sexually selected traits if it affects the strength of directional selection. A key social parameter which affects the intensity of, and sometimes predicts the response to, mating competition is the operational sex ratio (OSR; ratio of receptive males to females). 2. How the OSR affects selection for specific male traits is poorly understood. It is also unclear how sexual selection is affected by interactions between the OSR and environmental factors, such as habitat complexity, that alter key male-female interactions such as mate encounter rates. 3. Here, we experimentally manipulated the OSR and habitat complexity and quantified sexual selection on male mosquitofish (Gambusia holbrooki) by directly measuring male reproductive success (i.e. paternity). 4. We show that, despite a more equitable sharing of paternity (i.e. higher levels of multiple paternity) under a male-biased OSR, selection on focal male traits was unaffected by the OSR or habitat complexity. Instead, sexual selection consistently, and significantly, favoured smaller bodied males, males with higher genome wide heterozygosity (based on >3000 SNP markers), and males with a relatively long gonopodium (intromittent organ).
Data from: Evidence of opposing fitness effects of parental heterozygosity and relatedness in a critically endangered marine turtle?
负责人:
关键词:
heterozygosity-fitness correlations;microsatellites;Eretmochelys imbricata;hawksbill turtle;Outbreeding depression;inbreeding depression;negative heterozygosity-fitness correlations
DOI:
doi:10.5061/dryad.6697t
摘要:
of conservation concern. Heterozygosity-fitness correlations (HFCs) have been widely used to study this link in wild populations, where key parameters that affect bot
Data from: Positive selection of deleterious alleles through interaction with a sex-ratio suppressor gene in African buffalo: a plausible new mechanism for a high frequency anomaly
负责人:
关键词:
bovine tuberculosis;sexually-antagonistic gene;HFC;Heterozygosity-fitness correlation;Y chromosome;sex-ratio distorter;sexually-antagonistic allele;allele cline;BTB;Cline;selection;African buffalo;Syncerus caffer;microsatellite;deleterious allele;sex-ratio suppressor
DOI:
doi:10.5061/dryad.23d13
摘要:
Although generally rare, deleterious alleles can become common through genetic drift, hitchhiking or reductions in selective constraints. Here we present a possible new mechanism that explains the attainment of high frequencies of deleterious alleles in the African buffalo (Syncerus caffer) population of Kruger National Park, through positive selection of these alleles that is ultimately driven by a sex-ratio suppressor. We have previously shown that one in four Kruger buffalo has a Y-chromosome profile that, despite being associated with low body condition, appears to impart a relative reproductive advantage, and which is stably maintained through a sex-ratio suppressor. Apparently, this sex-ratio suppressor prevents fertility reduction that generally accompanies sex-ratio distortion. We hypothesize that this body-condition-associated reproductive advantage increases the fitness of alleles that negatively affect male body condition, causing genome-wide positive selection of these alleles. To investigate this we genotyped 459 buffalo using 17 autosomal microsatellites. By correlating heterozygosity with body condition (heterozygosity-fitness correlations), we found that most microsatellites were associated with one of two gene types: one with elevated frequencies of deleterious alleles that have a negative effect on body condition, irrespective of sex; the other with elevated frequencies of sexually antagonistic alleles that are negative for male body condition but positive for female body condition. Positive selection and a direct association with a Y-chromosomal sex-ratio suppressor are indicated, respectively, by allele clines and by relatively high numbers of homozygous deleterious alleles among sex-ratio suppressor carriers. This study, which employs novel statistical techniques to analyse heterozygosity-fitness correlations, is the first to demonstrate the abundance of sexually-antagonistic genes in a natural mammal population. It also has important implications for our understanding not only of the evolutionary and ecological dynamics of sex-ratio distorters and suppressors, but also of the functioning of deleterious and sexually-antagonistic alleles, and their impact on population viability.
Data from: Oxidative stress-mediated NF?B phosphorylation upregulates p62/SQSTM1 and promotes retinal pigmented epithelial cell survival through increased autophagy
负责人:
关键词:
autophagy;RPE;ATG10;p62\/SQSTM1;Age-related macular degeneration;NF?B p65;Oxidative stress
DOI:
doi:10.5061/dryad.2gn8c
摘要:
and p65 phosphorylation when RPE was challenged by H2O2 but not when by Lactacystin. p62 protein but not RNA levels are elevated in APOE4-HFC AMD mouse model, suggesting
OECD Environment Statistics, 1980-2013
负责人:
关键词:
DOI:
doi:10.5255/ukda-sn-7784-1
摘要:
and lignite, rice paddies, agriculture and leaks from natural gas pipelines), nitrous oxide (N2O), hydrofluorocarbons (HFCs), perfluorocarbons (PFC
OECD Environment Statistics, 1980-2019
负责人:
关键词:
DOI:
doi:10.5255/ukda-sn-7784-2
摘要:
and lignite, rice paddies, agriculture and leaks from natural gas pipelines), nitrous oxide (N2O), hydrofluorocarbons (HFCs), perfluorocarbons (PFC
OECD Environment Statistics, 1950-2017
负责人:
关键词:
DOI:
doi:10.5255/ukda-sn-7784-3
摘要:
, hydrofluorocarbons (HFCs), perfluorocarbons (PFCs) and sulphur hexafluoride (SF6) for GHG and for other pollutants emissions data refer to emissions of sulphur oxides

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