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Data from: microCT-based phenomics in the zebrafish skeleton reveals virtues of deep phenotyping in a distributed organ system
- 负责人:
- DOI:
- doi:10.5061/dryad.pm41d
- 摘要:
- criminating mutant populations compared to analyzing individual vertebrae in isolation. We identify phenotypes associated with human brittle bone disease
Data from: Clinically relevant cranio-caudal patterns of cervical cord atrophy evolution in MS
- 负责人:
- DOI:
- doi:10.5061/dryad.2h2g698
- 摘要:
- rly RRMS (disease duration<5 years) and CIS patients. Late RRMS (disease duration>5 years) showed significant cord atrophy vs early RRMS (p=0.02
Data from: Genetic mapping of novel loci affecting canine blood phenotypes
- 负责人:
- DOI:
- doi:10.5061/dryad.30c8p
- 摘要:
- d for disease studies. For many of these dogs, additional clinical phenotypes are available, such as hematological and clinical chemistry results collected duri
Data from: ApoE is a correlate of phenotypic heterogeneity in Alzheimer’s disease in a national cohort
- 负责人:
- DOI:
- doi:10.5061/dryad.69qg1c0
- 摘要:
- Objective: To compare the proportion of APOE?4 genotype carriers in aphasic versus amnestic variants of Alzheimer’s disease (AD). Method
Data from: Effect of trait's expression level on single-step genomic evaluation of resistance to Dothistroma needle blight
- 负责人:
- DOI:
- doi:10.5061/dryad.qfttdz0d7
- 摘要:
- orly phenotyped disease traits also showed very high accuracy in terms of correlation of predicted genomic breeding values with pedigree-based counterparts. Howeve
Data from: Phenotypic interactions between tree hosts and invasive forest pathogens in the light of globalization and climate change
- 负责人:
- Stenlid, Jan
- 关键词:
- DOI:
- doi:10.5061/dryad.1182k
- 摘要:
- , underlining the need to include the roles of the environment and the phenotype in host–pathogen interactions when predicting disease impacts. We emph
Data from: The clinical, histological, and genotypic spectrum of SEPN1-related myopathy: a case series
- 负责人:
- DOI:
- doi:10.5061/dryad.nzs7h44nj
- 摘要:
- antly associated with disease severity (p=0.017).? SEPN1-RM was more severe and progressive than previously thought, leading to loss of ambulation in 10% case
Data from: Using the generalized index of dissimilarity to detect gene-gene interactions in multi-class phenotypes
- 负责人:
- 关键词:
- DOI:
- doi:10.5061/dryad.63nd8
- 摘要:
- To find genetic association between complex diseases and phenotypic traits, one important procedure is conducting a joint analysis. Multifactor
Data from: Metabolite profile of a mouse model of Charcot-Marie-Tooth type 2D neuropathy: implications for disease mechanisms and interventions
- 负责人:
- Burgess, Robert W.
- DOI:
- doi:10.5061/dryad.ng07t
- 摘要:
- Charcot-Marie-Tooth disease encompasses a genetically heterogeneous class of heritable polyneuropathies that result in axonal degeneration
Data from: Trade-offs and evolution of thermal adaptation in the Irish potato famine pathogen Phytophthora infestans
- 负责人:
- DOI:
- doi:10.5061/dryad.024t1
- 摘要:
- and biotic interactions, including diseases. In this study, we used a combination of statistical genetics, experimental evolution and common garden expe