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Data from: Postmortem neurodegenerative markers and trajectories of decline in cognitive systems
- 负责人：
- DOI：
- doi:10.5061/dryad.mf7hk2q
- 摘要：
- , and hippocampal sclerosis were associated with impairment in other cognitive domains but the association of TDP-43 pathology with cognition continued to be mainly confined
Data from: CSF biomarkers of neuroinflammation and cerebrovascular dysfunction in early Alzheimer's disease
- 负责人：
- DOI：
- doi:10.5061/dryad.5f82b32
- 摘要：
- and clinical disease progression over time. Methods: The study included cognitively unimpaired elderly (n=508), patients with mild cognitive impairment (MCI
Data from: Catechol-O-Methyltransferase moderates effect of stress mindset on affect and cognition
- 负责人：
- DOI：
- doi:10.5061/dryad.2sk69c4
- 摘要：
- and subsequent cognitive tasks. The associations of the COMT rs4680 polymorphism with the effect of stress mindset video manipulations on cognitive and affective
Data from: Measuring engagement in advance care planning: a cross-sectional multicentre feasibility study.
- 负责人：
- DOI：
- doi:10.5061/dryad.1ng8c
- 摘要：
- ngs. Participants: A convenience sample of patients without cognitive impairment who could speak and read English was recruited. Patients 50 years and older wer
Data from: Amyloid and cerebrovascular burden divergently influence brain functional network changes over time
- 负责人：
- DOI：
- doi:10.5061/dryad.v5h2fd7
- 摘要：
- ) and executive control network (ECN) functional connectivity (FC) changes in mild cognitive impairment (MCI) patients. Methods: We studied 30 amnestic (aMCI) and 55
Data from: Tactile and proprioceptive dysfunction differentiates cervical dystonia with and without tremor
- 负责人：
- DOI：
- doi:10.5061/dryad.2264mf4
- 摘要：
- Objective: To determine if different phenotypes of cervical dystonia (CD) express different types and levels of somatosensory impairment. Methods
Data from: Big data analysis of genes associated with neuropsychiatric disorders in an Alzheimer's disease animal model
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.408d6f0
- 摘要：
- Alzheimer’s disease is a neurodegenerative disease characterized by the impairment of cognitive function and loss of memory, affecting millions
Data from: TAK-071, a muscarinic M1 receptor positive allosteric modulator, attenuates scopolamine-induced quantitative electroencephalogram
- 负责人：
- Kurimoto, Emi
- 关键词：
- Monkeys Cognitive impairment Alzheimer's disease Electroencephalography Biomarkers Animal cognition Cholinergics Oral administration
- DOI：
- doi:10.5061/dryad.qp313np
- 摘要：
- ’s disease, dementia with Lewy bodies, and schizophrenia. TAK-071 is an M1-selective positive allosteric modulator that improves cognitive deficits induced
Data from: Distinct epileptiform abnormalities are associated with clinical seizures in Alzheimer’s disease
- 负责人：
- DOI：
- doi:10.5061/dryad.8gtht76kc
- 摘要：
- cognitively normal elderly healthy controls (HC), 41 early-stage AD participants with no history or risk factors for epilepsy (AD-NoEp), and 15 early-stage AD
Data from: Sex differences in CSF biomarkers vary by Alzheimer’s disease stage and APOE epsilon 4 genotype
- 负责人：
- DOI：
- doi:10.5061/dryad.ttdz08ktw
- 摘要：
- and APOEe4 genotype into account. Method: We included participants (n=1801) with probable AD dementia (n=937), Mild Cognitive Impairment (MCI; n=437
