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Data from: Longevity is determined by ETS transcription factors in multiple tissues and diverse species
- 负责人:
- DOI:
- doi:10.5061/dryad.5qv9750
- 摘要:
- Ageing populations pose one of the main public health crises of our time. Reprogramming gene expression by altering the activities of sequence
Data from: Antagonistic pleiotropy and mutation accumulation contribute to age-related decline in stress response
- 负责人:
- DOI:
- doi:10.5061/dryad.vq087
- 摘要:
- of age-related changes associated with senescence is likely influenced by mutation accumulation (MA) and antagonistic pleiotropy (AP). MA predicts that age
Data from: Gene expression changes in male accessory glands during ageing are accompanied by reproductive decline in Drosophila melanogaster
- 负责人:
- DOI:
- doi:10.5061/dryad.7m644
- 摘要:
- Senescence is accompanied by loss of reproductive functions. Here we studied reproductive ageing in Drosophila melanogaster males and asked whether
Data from: Deleterious consequences of antioxidant supplementation on lifespan in a wild-derived mammal
- 负责人:
- DOI:
- doi:10.5061/dryad.31cc4
- 摘要:
- -related diseases, its causative role in ageing is controversial. In particular, studies that have attempted to modulate ROS-induced damage, either upwards or downward, usi
Data from: Long-lived rodents reveal signatures of positive selection in genes associated with lifespan
- 负责人:
- Sahm, Arne
- 关键词:
- Positive selection African mole-rats Naked mole-rat Evolution of longevity lifespan Blind mole rat Spalax IGF1 RHEB RHEBL1
- DOI:
- doi:10.5061/dryad.75b406n
- 摘要:
- t fits the antagonistic pleiotropy theory of aging. Moreover, we found the PSGs to be enriched for genes known to be related to aging. Among these
Data from: Reduced lifespan and increased ageing driven by genetic drift in small populations
- 负责人:
- DOI:
- doi:10.5061/dryad.1vv8v
- 摘要:
- indeed exists among populations of Daphnia magna, and that ageing is accelerated in small populations. Additional results suggest that this is due to increased
Data from: Offspring provisioning explains clone specific maternal age effects on life history and lifespan in the water flea, Daphnia pulex
- 负责人:
- DOI:
- doi:10.5061/dryad.3k8c0
- 摘要:
- Genetic inheritance underpins evolutionary theories of aging, but the role that nongenetic inheritance plays is unclear. Parental age reduces
Data from: Senescence rates and late adulthood reproductive success are strongly influenced by personality in a long lived seabird
- 负责人:
- DOI:
- doi:10.5061/dryad.sn711
- 摘要:
- Studies are increasingly demonstrating that individuals differ in their rate of ageing, and this is postulated to emerge from a trade-off bet
Data from: Evolution of differential maternal age effects on male and female offspring development and longevity
- 负责人:
- DOI:
- doi:10.5061/dryad.2320n
- 摘要:
- 1. Maternal age effects on life-history traits, including longevity, are widespread and can be seen as a manifestation of ageing. However, littl
Data from: Senescence in duckweed: age-related declines in survival, reproduction, and offspring quality
- 负责人:
- DOI:
- doi:10.5061/dryad.t938n
- 摘要:
- on the evolutionary biology of senescence should devote more attention to offspring quality. This often unrecognized component of fitness may change with age – as we have sh