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Data from: The basis of antagonistic pleiotropy in hfq mutations that have opposite effects on fitness at slow and fast growth rates
- 负责人：
- DOI：
- doi:10.5061/dryad.5bd50
- 摘要：
- Mutations beneficial in one environment may cause costs in different environments, resulting in antagonistic pleiotropy. Here we describe a nove
Data from: Stress-induced mutagenesis and complex adaptation
- 负责人：
- DOI：
- doi:10.5061/dryad.3066j
- 摘要：
- Because mutations are mostly deleterious, mutation rates should be reduced by natural selection. However, mutations also provide the raw material
Data from: Mutation rules and the evolution of sparseness and modularity in biological systems
- 负责人：
- DOI：
- doi:10.5061/dryad.75180
- 摘要：
- varying goals), or when connections are costly. Here, we studied the origin of modularity and sparseness focusing on the nature of the mutation process, ra
Data from: Known mutator alleles do not markedly increase mutation rate in clinical Saccharomyces cerevisiae strains
- 负责人：
- DOI：
- doi:10.5061/dryad.125p3
- 摘要：
- t in asexual populations, mutator alleles, which cause high mutation rates, can fix due to linkage with beneficial mutations. This phenomenon has been demons
Data from: The rate and effects of spontaneous mutation on fitness traits in the social amoeba, Dictyostelium discoideum
- 负责人：
- DOI：
- doi:10.5061/dryad.8f6nq
- 摘要：
- on of effects of spontaneous mutations affecting eight putative fitness traits. We found that the per generation mutation rate for most fitness components
Data from: Fitness decline in spontaneous mutation accumulation lines of Caenorhabditis elegans with varying effective population sizes
- 负责人：
- DOI：
- doi:10.5061/dryad.v5012
- 摘要：
- The rate and fitness effects of new mutations have been investigated by mutation accumulation (MA) experiments in which organisms are mainta
Data from: Effects of genotype on rates of substitution during experimental evolution
- 负责人：
- DOI：
- doi:10.5061/dryad.36td2
- 摘要：
- on size, mutation rates, or in the distribution of fitness effects (DFE) of available beneficial mutations. By whole genome sequencing of Escherichia coli populations
Data from: Fitness of Arabidopsis thaliana mutation accumulation lines whose spontaneous mutations are known
- 负责人：
- DOI：
- doi:10.5061/dryad.rk5fp6n9
- 摘要：
- ) to mutation effects on fitness implies spatial and/or temporal variation in selection on new mutations and could contribute to the maintenance
Data from: Validation of targeted next-generation sequencing for RAS mutation detection in FFPE colorectal cancer tissues: comparison
- 负责人：
- DOI：
- doi:10.5061/dryad.3447g
- 摘要：
- Objective: To validate the targeted next-generation sequencing (NGS) platform-Ion Torrent PGM for KRAS exon 2 and expanded RAS mutations detecti
Data from: Fitness decline under osmotic stress in Caenorhabditis elegans populations subjected to spontaneous mutation accumulation at varying
- 负责人：
- DOI：
- doi:10.5061/dryad.d6441s7
- 摘要：
- The consequences of mutations for population fitness depends on their individual selection coefficients and the effective population size. An earlier
