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Data from: Synthesis of gypsogenin derivatives with capabilities to arrest cell cycle and induce apoptosis in human cancer cells
- 负责人：
- DOI：
- doi:10.5061/dryad.35j3j
- 摘要：
- , 13C NMR, and LC-MS spectroscopic data. In MTT assays nearly all the compounds displayed good cytotoxicity in the low ?M range for several human tumour cell
Data from: Teratological and behavioral screening of the National Toxicology Program 91-compound library in zebrafish (Danio rerio)
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- 关键词：
- DOI：
- doi:10.5061/dryad.r841282
- 摘要：
- by the National Toxicology Program (NTP) for developmental toxicity. This library contained 86 unique chemicals that included negative controls, flame retardants
Data from: Identification of any structure-specific hepatotoxic potential of different pyrrolizidine alkaloids using Random Forest
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- 关键词：
- DOI：
- doi:10.5061/dryad.qn7d3
- 摘要：
- and exhibit developmental toxicity. Only for very few PAs, in vitro and in vivo investigations have characterised their toxic potential. However, these
Data from: Application of benchmark concentration (BMC) analysis on zebrafish data – a new perspective for quantifying toxicity in alternative
- 负责人：
- 关键词：
- Danio rerio
- DOI：
- doi:10.5061/dryad.rt7f0b0
- 摘要：
- Over the past decade, the zebrafish is increasingly being used as a model to screen for chemical-mediated toxicities including developmental toxicity
Data from: Psychostimulant-induced testicular toxicity in mice: evidence of cocaine and caffeine effects on the local dopaminergic system
- 负责人：
- DOI：
- doi:10.5061/dryad.qh03c
- 摘要：
- Several organ systems can be affected by psychostimulant toxicity. However, there is not sufficient evidence about the impact of psychostimulant
Data from: Phosphorescence monitoring of hypoxic microenvironment in solid-tumors to evaluate chemotherapeutic effects using the hypoxia-sensitive
- 负责人：
- DOI：
- doi:10.5061/dryad.pb7j7
- 摘要：
- al staining to confirm imaging results. Results: BTP did not feature obvious cytotoxicity for cells, and tumor growth in low-dose metronomic cisplatin treated mice was sig
Data from: Medically important differences in snake venom composition are dictated by distinct postgenomic mechanisms
- 负责人：
- DOI：
- doi:10.5061/dryad.1j292
- 摘要：
- of toxin transcription, translation, and their posttranslational modification have a substantial impact upon the resulting venom protein mixture. Notably
Data from: Combined exposure to sublethal concentrations of an insecticide and a fungicide affect feeding, ovary development and longevity
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- DOI：
- doi:10.5061/dryad.895pn6p
- 摘要：
- Pollinators in agroecosystems are often exposed to pesticide mixtures. Even at low concentrations, the effects of these mixtures on bee populations
Data from: Identification of reactive intermediate formation and bioactivation pathways in Abemaciclib metabolism by LC–MS/MS: in vitro metabolic
- 负责人：
- DOI：
- doi:10.5061/dryad.71f1s18
- 摘要：
- to the tertiary nitrogen atoms of piperazine ring can aid in reducing toxic side effects of ABC. No previous articles were found about in vitro metabolic
Data from: An integrative computational approach for a prioritization of key transcription regulators associated with nanomaterial-induced toxicity
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- 关键词：
- DOI：
- doi:10.5061/dryad.3b025hh
- 摘要：
- adverse health effect of nanomaterials (NMs) are complex, time consuming and expensive. In order to develop new prediction tests for nanotoxicity evaluation
