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Data from: Sequence entropy of folding and the absolute rate of amino acid substitutions
负责人:
关键词:
protein evolution;epistasis;Coevolution;substitution rate;Contingency;transition state theory;statistical mechanics;evolutionary Stokes shift;entrenchment
DOI:
doi:10.5061/dryad.7b8vb
摘要:
Adequate representations of protein evolution should consider how the acceptance of mutations depends on the sequence context in which they aris
Soil and yield in legume niche exploration
负责人:
关键词:
DOI:
doi:10.25502/rn3q-m491/d
摘要:
The project aims at facilitating the smart integration and use of multi-purpose legumes, providing food, protein, feed, fuel, and/or organic matte
Data from: The genetic architecture of biofilm formation in a clinical isolate of Saccharomyces cerevisiae
负责人:
关键词:
colony morphology;Bulk Segregant Analysis;cAMP-PKA;Biofilm;Natural Variation;Saccharomyces cerevisiae
DOI:
doi:10.5061/dryad.mn71g
摘要:
most closely associated with each locus. Of these candidate genes, six are members of the cyclic AMP-protein kinase A pathway, an evolutionarily
Data from: An experimental analysis of the molecular effects of trastuzumab (herceptin) and fulvestrant (falsodex), as single agents
负责人:
关键词:
trastuzumab;fulvestrant;BT-474 cell line;ZR-75-1 cell line;mouse tumor xenografts
DOI:
doi:10.5061/dryad.7mp37
摘要:
or in combination on tumor growth as well as on expression of the protein p-MED1 expressed in in vivo mouse xenograft models was also examined. Result
Data from: Izumo1 and Juno: the evolutionary origins and coevolution of essential sperm-egg binding partners
负责人:
关键词:
positive selection;Izumo1 and Izumo Family;gene family evolution;Juno and Folate Receptor Family;Reproduction and Fertilization;Coevolution
DOI:
doi:10.5061/dryad.gh208
摘要:
by positive Darwinian selection despite vital, well-conserved, reproductive functions. Izumo1 is the only essential sperm–egg fusion protein currently known on mammalian sperm
Data from: Glutathione S-transferase protein expression in different life stages of zebrafish (Danio rerio)
负责人:
关键词:
biotransformation;multiple reaction monitoring;Danio rerio;targeted proteomics;GST;mass spectrometry
DOI:
doi:10.5061/dryad.5s32v
摘要:
defense mechanisms in zebrafish exists on the transcriptional and enzyme activity level, little is known about the protein expression of xenobiotic
Data from: Carotenoid metabolic profiling and transcriptome-genome mining reveal functional equivalence among blue-pigmented copepods
负责人:
关键词:
Acartia fossae;Transcriptomics;Oikopleura dioica;molecular evolution;Bioinfomatics\/Phyloinfomatics;Community Ecology;Behavior\/Social Evolution;Adaptation
DOI:
doi:10.5061/dryad.mm18b
摘要:
own that carotenoid protein complexes are responsible for blue coloration in crustaceans. Therefore, we performed carotenoid metabolic profiling using bot
Data from: Spatiotemporal changes in the distribution of LHFPL5 in mice cochlear hair bundles during development and in the absence of PCDH15
负责人:
关键词:
Mechanoelectrical Transduction;cochlea;LHFPL5;development;Hair cell
DOI:
doi:10.5061/dryad.q3b16
摘要:
subunit 1 (TMC1), lipoma HMGIC fusion partner-like 5 protein (LHFPL5) and protocadherin 15 (PCDH15), a lower-end component of the tip link. TMC1 inte
Data from: Diagnostic performance of alpha-fetoprotein, protein induced by vitamin K absence, osteopontin, Dickkopf-1 and its combinations
负责人:
关键词:
osteopontin;alpha-fetoprotein;dickkopf-1;Hepatocellular carcinoma;PIVKA-II
DOI:
doi:10.5061/dryad.3n901
摘要:
. As complementary biomarkers, protein induced by vitamin K absence (PIVKA-II), osteopontin (OPN), and Dickkopf-1 (DKK-1) have been proposed. This study aimed
Data from: Cavin-3 dictates the balance between ERK and Akt signaling
负责人:
关键词:
Mus musculus;Cavin-3;hSRBC;PRKCDBP;Homo Sapiens;Akt;aerobic glycolysis;caveolae;ERK
DOI:
doi:10.5061/dryad.4950k
摘要:
Cavin-3 is a tumor suppressor protein of unknown function. Using a combination of in vivo knockout and in vitro gain/loss of function appro

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