Proinsulin-transferrin fusion protein as a liver targeting insulin therapeutic in Type 1 diabetes treatment

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Pharmaceutical Sciences proinsulin-transferrin fusion protein liver targeting diabetes long-acting insulin therapeutic

DOI：

doi:10.25549/usctheses-c40-250950

摘要：

d drugs achieved anti-diabetic effect by regulation of glucose metabolism related enzymes, e.g., liver-selective glucokinase activator or by targeti

Data from: Testosterone activates sexual dimorphism including male-typical carotenoid but not melanin plumage pigmentation in a female bird

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plumage color;testosterone;carotenoids;melanins;Malurus melanocephalus;bill color;sexual dimorphism

DOI：

doi:10.5061/dryad.gf46s

摘要：

In males it is frequently testosterone (T) that activates the expression of sexually selected morphological and behavioral displays, but the role

Data from: Variation in the frequency and extent of hybridization between Leucosceptrum japonicum and L. stellipilum (Lamiaceae) in the central Japanese

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mixed population;Leucosceptrum japonicum;extent of hybridization;frequency of hybridization;nuclear microsatellites;Leucosceptrum stellipilum

DOI：

doi:10.5061/dryad.7sf28

摘要：

kely explanation is that variation in exogenous (ecological) selection among populations might contribute to differences in frequency and extent of hybridizati

Data from: Genomic and phenotypic architecture of a spruce hybrid zone (Picea sitchensis x P. glauca)

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Picea glauca;climate change;Picea sitchensis;hybridization;Ecological Genetics;Adaptation

DOI：

doi:10.5061/dryad.s11b6

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. Our results indicated that exogenous selection appeared to play a strong role in the distribution and structure of this hybrid zone, indicati

Data from: Thermal plasticity in farmed, wild and hybrid Atlantic salmon during early development: has domestication caused diverge

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reaction norms;Growth;local adaptation;Salmo salar;Escapees;Phenotypic Plasticity;salmonids;Ecology;Salmon strains;introgression;survival

DOI：

doi:10.5061/dryad.562ft

摘要：

indicating that phenotypic plasticity instead of thermal adaption has been selected for in Atlantic salmon.